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由 Y 群脑膜炎奈瑟菌宫内传播引起的致命性早发性败血症。

Fatal Early-onset Sepsis Caused by Intrauterine Transmission of Serogroup Y Meningococcus.

机构信息

From the Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, University Medical Centre Rotterdam, Rotterdam, The Netherlands.

Division of Neonatology, Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, University Medical Centre Rotterdam, Rotterdam, The Netherlands.

出版信息

Pediatr Infect Dis J. 2022 Dec 1;41(12):e517-e519. doi: 10.1097/INF.0000000000003722. Epub 2022 Sep 28.

DOI:10.1097/INF.0000000000003722
PMID:36375102
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9645541/
Abstract

Infections by meningococcal species are extremely rare in the first days of life. We present a fatal case of early-onset sepsis presenting at birth, caused by intrauterine transmission of serogroup Y N. meningitidis, evidenced clinically and histologically by corresponding chorioamnionitis and N. meningitidis-positive amniotic fluid. This case confirms a long-standing suspicion that N. meningitidis can be transmitted in utero.

摘要

脑膜炎奈瑟菌感染在生命的最初几天极为罕见。我们报告了一例出生时即发生的早发性败血症的致命病例，由 Y 群脑膜炎奈瑟菌通过宫内传播引起，临床上和组织学上均表现为相应的绒毛膜羊膜炎和脑膜炎奈瑟菌阳性羊水。该病例证实了长期以来的怀疑，即脑膜炎奈瑟菌可在宫内传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5ab/9645541/45604a076a97/inf-41-e517-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5ab/9645541/45604a076a97/inf-41-e517-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d5ab/9645541/45604a076a97/inf-41-e517-g001.jpg

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