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2022 年 HIV-1 耐药突变更新。

2022 update of the drug resistance mutations in HIV-1.

机构信息

University Medical Center Utrecht, The Netherlands and Ezintsha, University of the Witwatersrand, Johannesburg, South Africa.

Pierre et Marie Curie University and Pitié-Salpêtrière Hospital, Paris, France.

出版信息

Top Antivir Med. 2022 Oct;30(4):559-574.

Abstract

The 2022 edition of the IAS-USA drug resistance mutations list updates the Figure last published in September 2019. The mutations listed are those that have been identified by specific criteria for evidence and drugs described. The Figure is designed to assist practitioners to identify key mutations associated with resistance to antiretroviral drugs, and therefore, in making clinical decisions regarding antiretroviral therapy.

摘要

2022 年版的 IAS-USA 耐药突变列表更新了最后一次发布于 2019 年 9 月的图表。列表中的突变是根据证据和描述的药物的具体标准确定的。该图表旨在帮助临床医生识别与抗逆转录病毒药物耐药相关的关键突变,从而做出抗逆转录病毒治疗的临床决策。

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