接种 COVID-19 疫苗前后的精神症状：一项住院精神分裂症患者的队列研究。
Psychiatric symptoms before and after COVID-19 vaccination: A cohort study of hospitalized schizophrenia patients.
机构信息
Tianjin Anding Hospital and Mental Health Center of Tianjin Medical University, Tianjin 300222, China.
Tianjin Jianhua Hospital, Tianjin 300393, China.
出版信息
Asian J Psychiatr. 2022 Dec;78:103319. doi: 10.1016/j.ajp.2022.103319. Epub 2022 Nov 11.
Abstract
This study aimed to examine the impact of COVID-19 vaccination on the psychiatric symptoms of hospitalized schizophrenia patients and to evaluate the association between the severity of psychiatric symptoms and the COVID-19 vaccination decision. We assessed the psychiatric symptoms of 330 hospitalized schizophrenia patients who accepted the vaccine and 114 patients who declined the vaccine option with PANSS before and after vaccination. We showed that the unwillingness to receive the vaccine is correlated with a higher level of psychiatric symptoms. COVID-19 vaccination is associated with slight deterioration of the schizophrenia symptoms of elderly hospitalized patients.
摘要
这项研究旨在探讨 COVID-19 疫苗接种对住院精神分裂症患者精神症状的影响，并评估精神症状严重程度与 COVID-19 疫苗接种决策之间的关系。我们评估了 330 名接受疫苗和 114 名拒绝疫苗的住院精神分裂症患者的精神症状，这些患者在接种前后都接受了 PANSS 评估。结果表明，不愿意接种疫苗与更高水平的精神症状有关。COVID-19 疫苗接种与老年住院患者精神分裂症症状的轻微恶化有关。
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