Department of Cardiology and Cardiovascular Surgery, Children's National Hospital, The George Washington University, Washington, DC, USA.
Department of Pediatric Cardiology, Monroe Carell Jr. Children's Hospital, Nashville, Tennessee, USA.
Pediatr Transplant. 2022 Dec;26(8):e14392. doi: 10.1111/petr.14392.
This manuscript outlines a clinical approach to vasoplegia incorporating the current state of knowledge regarding vasoplegia in pediatric patients immediately post-transplant and to identify modifiable factors both pre- and post-transplant that may reduce post-operative morbidity, end-organ dysfunction, and mortality. Centers participating in the Pediatric Heart Transplant Society (PHTS) were asked to provide their internal protocols and rationale for vasoplegia management, and applicable adult and pediatric data were reviewed. The authors synthesized the above protocols and literature into the following description of clinical approaches to vasoplegia highlighting areas of both broad consensus and of significant practice variation.
本手稿概述了一种血管扩张综合征的临床处理方法，其中纳入了当前关于儿科患者移植后即刻血管扩张综合征的知识现状，并确定了移植前和移植后可能降低术后发病率、终末器官功能障碍和死亡率的可改变因素。要求参与儿科心脏移植协会（PHTS）的中心提供其血管扩张综合征管理的内部方案和原理，并审查了适用的成人和儿科数据。作者将上述方案和文献综合为血管扩张综合征的临床处理方法描述，重点介绍了广泛共识和显著实践差异的领域。
