使用聚乙二醇和聚乳酸的三嵌段共聚物，用各种环糊精作为轮组件制备立构复合物和假聚轮烷。

Preparation of stereocomplex and pseudo-polyrotaxane with various cyclodextrins as wheel components using triblock copolymer of poly(ethylene glycol) and polylactide.

机构信息

Graduate School of Science and Technology, Division of Materials Science, Nara Institute of Science and Technology, Ikoma, Nara, 630-0192, Japan.

出版信息

Soft Matter. 2022 Nov 30;18(46):8885-8893. doi: 10.1039/d2sm01124g.

DOI:10.1039/d2sm01124g

PMID:36377482

Abstract

The ABA-type triblock-copolymers (BCPs) of polylactide (PLA) and poly(ethylene glycol) (PEG) were synthesized as axle components for rotaxane formation. It is known that α-cyclodextrin (CD) exists near the PEG moiety in pseudo-polyrotaxane (PPRX), and the PLA moiety can form a stereocomplex (SC), by mixing with L- and D-isomers. In this study, various CDs, including β-CD and γ-CD, were used as wheel components, and effects of CD structures on both PPRX and SC formations were studied. The solubility of CDs is influenced to form the PPRX, resulting in differing numbers of CDs in the axle. PPRX structures were investigated by H NMR, NOESY, and DOSY, and SC structures were investigated by FT-IR and XRD. Their thermal properties were also evaluated by DSC and TGA, to consider the physical properties of the simultaneous formation of PPRX and SC. This study gave insight into the complicated host-guest and polymer-polymer interactions.

摘要

ABA 型嵌段共聚物（BCPs）的聚乳酸（PLA）和聚乙二醇（PEG）作为轮烷形成的轴组件被合成。众所周知，在假聚轮烷（PPRX）中，α-环糊精（CD）存在于聚乙二醇部分附近，而 PLA 部分可以与 L-和 D-异构体形成立体复合物（SC）。在这项研究中，各种 CD，包括β-CD 和γ-CD，被用作轮组件，研究了 CD 结构对 PPRX 和 SC 形成的影响。CD 的溶解度影响 PPRX 的形成，导致轴中 CD 的数量不同。通过 H NMR、NOESY 和 DOSY 研究 PPRX 结构，通过 FT-IR 和 XRD 研究 SC 结构。还通过 DSC 和 TGA 评估它们的热性能，以考虑 PPRX 和 SC 同时形成的物理性质。这项研究深入了解了复杂的主体-客体和聚合物-聚合物相互作用。