Arumugam Sathishkumar, Ramessh Chelvi, Kaliappan Gobala Krishnana, Govindhan Rajiv, Prakasam Sebastein Belciya, Murugan Silambarasan, Pandian Sureshkumar, Asgar Ebadollahi, Ravi Prasanth
Department of Agronomy, Agriculture and Research Institute, Madurai, India.
Department of Crop Management, Kumaraguru Institute of Agriculture, Erode, India.
Chem Biol Drug Des. 2023 Jan;101(1):158-174. doi: 10.1111/cbdd.14158. Epub 2022 Nov 15.
Lycopersene is a stable and safe triterpenoid. Lycopersen had utilized as an antioxidant, antimutagenic, antiproliferative, cytotoxicity, antibacterial and pesticide. Obtaining pure Lycopersene from natural sources is very important for fundamental research and the above applications. The present overview provides an up-to-date and comprehensive summary of the various methods used for extraction, isolation and purification of Lycopersene from natural sources with its applications in food, cosmetics and pharmaceutical fields. Many different extraction methods ranging from conventional techniques (e.g. Soxhlet extraction, Maceration and Rotary evaporator) and other advanced extraction technologies (e.g. Solid-phase microextraction, steam distillation with Clevenger, Clevenger apparatus, Chromatography on SiO column, centrifuge, sonication) had been used to obtain Lycopersene from flora and fauna. Purification techniques, alone or in combination, have been investigated for isolation and purification of Lycopersene from crude extracts in various natural sources. The review of Lycopersene identified cap areas like purity and application in various fields.
番茄三萜烯是一种稳定且安全的三萜类化合物。番茄三萜烯已被用作抗氧化剂、抗诱变剂、抗增殖剂、细胞毒性剂、抗菌剂和杀虫剂。从天然来源获取纯番茄三萜烯对于基础研究和上述应用非常重要。本综述提供了关于从天然来源提取、分离和纯化番茄三萜烯的各种方法及其在食品、化妆品和制药领域应用的最新且全面的总结。许多不同的提取方法,从传统技术(如索氏提取、浸渍法和旋转蒸发仪)到其他先进提取技术(如固相微萃取、用克莱文杰蒸馏器进行水蒸气蒸馏、克莱文杰装置、硅胶柱色谱法、离心机、超声处理),都已被用于从动植物中获取番茄三萜烯。已对单独或组合使用的纯化技术进行了研究,以从各种天然来源的粗提物中分离和纯化番茄三萜烯。对番茄三萜烯的综述确定了纯度和在各个领域的应用等关键领域。