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一项双盲对照临床试验,以评估使用Vrihatajivakadya油进行鼻腔治疗对偏头痛患者不同黏度的影响。

A double-blind controlled clinical trial to evaluate the effects of nasal therapy with Vrihatajivakadya oil on different viscosities in patients with migraine.

作者信息

Singh Sarvesh Kumar, Rajoria Kshipra, Kumar Avadhesh, Sharma Sanjeev

机构信息

Department of Panchakarma, National Institute of Ayurveda, Jaipur, India.

Department of Panchakarma, National Institute of Ayurveda, Jaipur, India.

出版信息

J Ayurveda Integr Med. 2023 Mar-Apr;14(2):100662. doi: 10.1016/j.jaim.2022.100662. Epub 2022 Nov 13.

DOI:10.1016/j.jaim.2022.100662
PMID:36384709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10307686/
Abstract

BACKGROUND

Migraine, characterized by pain of a specific type in one half of the head has a close resemblance with Ardhavabhedaka described in Ayurveda. Nasya karma (nasal therapy) with Vrihatajivakadya oil is indicated in Ardhavabhedaka. Low viscosity oil (LVO) and medium viscosity oil (MVO) prepared by Snehapaka (a specific Ayurveda method for preparation of oil) are advocated in different classical Ayurveda texts for N.karma.

THE OBJECTIVES

This study was done to assess the effects of Vrihatajivakadhya oil on different viscosities in N.karma for the better Ayurveda management of migraine.

MATERIAL AND METHODS

In this double-blind randomized controlled trial a total of 90 patients were randomly divided into two groups for N.karma with oil of different viscosities. In the group treated with LVO, 44 patients completed their treatment and one patient was lost in follow-up. In another group treated with MVO, 45 patients were enrolled and completed the intervention. N.karma was done with this oil in the dose of 6 drops per nostril for the duration of 14 days for each participant. The follow-up was done on the 15th day and 45th days. The assessment was done by the Migraine Disability Assessment Score (MIDAS) and Migraine Specific Quality of Life Assessment scale.

RESULT

During the trial, significant improvement in both the groups on both parameters was observed. No adverse event was noticed during the study.

CONCLUSION

N.karma with MVO had better improvement. No adverse event was noticed during the study. N.karma with these oils is effective and safe for migraine.

摘要

背景

偏头痛以头部一侧特定类型的疼痛为特征,与阿育吠陀中描述的半侧头痛极为相似。阿育吠陀指出,使用Vrihatajivakadya油进行滴鼻疗法(鼻腔治疗)可用于治疗半侧头痛。不同的阿育吠陀经典文献提倡使用由Snehapaka(一种特定的阿育吠陀油制备方法)制备的低粘度油(LVO)和中粘度油(MVO)进行滴鼻疗法。

目的

本研究旨在评估Vrihatajivakadhya油在不同粘度下进行滴鼻疗法对偏头痛的阿育吠陀治疗效果,以实现更好的治疗管理。

材料与方法

在这项双盲随机对照试验中,总共90名患者被随机分为两组,分别使用不同粘度的油进行滴鼻疗法。在使用LVO治疗的组中,44名患者完成了治疗,1名患者失访。在另一组使用MVO治疗的组中,45名患者入组并完成了干预。每位参与者每侧鼻孔滴入6滴该油,持续14天进行滴鼻疗法。在第15天和第45天进行随访。通过偏头痛残疾评估量表(MIDAS)和偏头痛特异性生活质量评估量表进行评估。

结果

在试验期间,两组在两个参数上均观察到显著改善。研究期间未观察到不良事件。

结论

使用MVO进行滴鼻疗法有更好的改善效果。研究期间未观察到不良事件。使用这些油进行滴鼻疗法对偏头痛有效且安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3819/10307686/bcfd76d2a815/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3819/10307686/bcfd76d2a815/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3819/10307686/bcfd76d2a815/gr1.jpg

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