Wang Sha, Jiang Yang, Lyu Jing, Li Jiajia, Diao Qingchun
Department of Dermatology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China.
Contact Dermatitis. 2023 Mar;88(3):201-205. doi: 10.1111/cod.14248. Epub 2022 Nov 28.
Cosmetic adverse reactions (CARs) are becoming widespread in China. However, a comprehensive analysis of data is lacking.
To analyse the clinical characteristics of patients with reported adverse reactions to cosmetics in Chongqing, China.
Cases with CARs reported to the Chongqing Adverse Drug Reaction Monitoring Centre System from 2017 to 2021 were analysed.
A total of 23 245 cases were identified, of which 94.5% were women. Contact dermatitis (84.3%) was the most common diagnosis of CARs, followed by acne (3.1%). The most frequently reported clinical signs were erythema (70.1%), followed by papules (35.5%). The majority of CARs were reported to be due to ordinary cosmetics (87.9%), of which 81.0% were skin care products and 7.1% were makeup products. Cosmetics with special functions constituted 12.2%, of these, skin whitening (54.0%) and sunscreen (28.0%) products were most frequently reported.
Our results suggest that adverse reactions to cosmetics are of concern in China, and dermatologists should actively identify and diagnose CARs. In addition, we should establish a convenient and effective model for collecting, reporting, and evaluating CARs.
化妆品不良反应（CARs）在中国正日益普遍。然而，目前缺乏对相关数据的全面分析。
分析中国重庆报告的化妆品不良反应患者的临床特征。
对2017年至2021年向重庆市药品不良反应监测中心系统报告的化妆品不良反应病例进行分析。
共识别出23245例病例，其中94.5%为女性。接触性皮炎（84.3%）是化妆品不良反应最常见的诊断，其次是痤疮（3.1%）。最常报告的临床体征是红斑（70.1%），其次是丘疹（35.5%）。大多数化妆品不良反应报告是由普通化妆品引起的（87.9%），其中81.0%是护肤品，7.1%是彩妆产品。具有特殊功能的化妆品占12.2%，其中，最常报告的是美白（54.0%）和防晒（28.0%）产品。
我们的结果表明，化妆品不良反应在中国值得关注，皮肤科医生应积极识别和诊断化妆品不良反应。此外，我们应建立一个方便有效的化妆品不良反应收集、报告和评估模式。
