Department for Orthopaedics and Trauma Surgery, University Hospital Bonn, Venusberg Campus 1, 53127, Bonn, Germany.
Department for Orthopaedics and Trauma Surgery, University Hospital Cologne, Cologne, Germany.
Arch Orthop Trauma Surg. 2023 Jun;143(6):3259-3269. doi: 10.1007/s00402-022-04692-y. Epub 2022 Nov 16.
Cartilage tissue has a very limited ability to regenerate. Symptomatic cartilage lesions are currently treated by various cartilage repair techniques. Multiple treatment techniques have been proposed in the last 30 years. Nevertheless, no single technique is accepted as a gold standard. Minced cartilage implantation is a newer technique that has garnered increasing attention. This procedure is attractive because it is autologous, can be performed in a single surgery, and is therefore given it is cost-effective. This narrative review provides an overview of the biological potential of current cartilage regenerative repair techniques with a focus on the translational evidence of minced cartilage implantation.
软骨组织的再生能力非常有限。目前,有多种软骨修复技术可用于治疗有症状的软骨损伤。在过去的 30 年中,已经提出了多种治疗技术。然而,目前尚无一种技术被公认为金标准。软骨碎块植入术是一种较新的技术,越来越受到关注。这种方法具有自体性,可以在单次手术中进行,因此具有成本效益,这使其具有吸引力。本综述概述了当前软骨再生修复技术的生物学潜力,并重点介绍了软骨碎块植入术的转化证据。