Luo Bei, Yang Yingying, Zhang Dapeng, Zhang Qing, Liu Zhichun, Wang Song, Shi Yudong, Xia Lei, Wang Jiawei, Liu Zhiwei, Geng Feng, Chen Changhao, Wen Xiangwang, Luo Xiangfen, Zhang Kai, Liu Huanzhong
School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei, China.
Department of Psychiatry, Chaohu Hospital of Anhui Medical University, Hefei, China.
Front Psychiatry. 2022 Oct 28;13:993284. doi: 10.3389/fpsyt.2022.993284. eCollection 2022.
Childhood trauma is closely related to the onset of depression and more severe depressive symptoms; however, the specific mechanisms are unclear. We aimed to examine the relationship between childhood trauma and sleep disorders in children and adolescents with depression and to explore further the role of sleep disorders in the relationship between childhood trauma and depression severity.
A total of 285 children and adolescents with depression completed all scale assessments, including the Childhood Trauma Questionnaire, Self-Reported Insomnia Severity Index and Epworth Sleepiness Scale, and the Center for Epidemiologic Studies Depression Scale. A simple mediation model was used as a theoretical model to examine whether sleep disorders could mediate the relationship between childhood trauma and depression severity.
Among children and adolescents with depression, childhood trauma is about 78.9%. Compared with patients without childhood trauma, patients with childhood trauma had a higher incidence of sleep disorders ( = 17.59, < 0.001), which were characterized by insomnia ( = 14.45, < 0.001), not hypersomnia ( = 2.77, = 0.096). Different childhood trauma subtypes significantly affected sleep disorders and insomnia (all < 0.05). Insomnia partially mediated the relationship between childhood trauma and depression severity, and the mediating effect accounted for 35.90%.
This study found a high rate of concurrent childhood trauma and insomnia among children and adolescents with depression. Insomnia, as a mediator between childhood trauma and depression severity, partially mediates the relationship.
童年创伤与抑郁症的发病及更严重的抑郁症状密切相关；然而，具体机制尚不清楚。我们旨在研究童年创伤与抑郁儿童及青少年睡眠障碍之间的关系，并进一步探讨睡眠障碍在童年创伤与抑郁严重程度关系中的作用。
共有285名抑郁儿童及青少年完成了所有量表评估，包括儿童创伤问卷、自我报告失眠严重程度指数、爱泼华嗜睡量表以及流行病学研究中心抑郁量表。采用简单中介模型作为理论模型，检验睡眠障碍是否能中介童年创伤与抑郁严重程度之间的关系。
在抑郁儿童及青少年中，童年创伤发生率约为78.9%。与无童年创伤的患者相比，有童年创伤的患者睡眠障碍发生率更高（ = 17.59， < 0.001），其特征为失眠（ = 14.45， < 0.001），而非嗜睡（ = 2.77， = 0.096）。不同的童年创伤亚型对睡眠障碍和失眠有显著影响（均 < 0.05）。失眠部分中介了童年创伤与抑郁严重程度之间的关系，中介效应占35.90%。
本研究发现抑郁儿童及青少年中童年创伤与失眠并发率较高。失眠作为童年创伤与抑郁严重程度之间的中介，部分中介了二者的关系。
