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病例报告:肺腺癌伴同步骨转移长期生存病例中生存与生活质量的平衡

Case report: A balance of survival and quality of life in long-term survival case of lung adenocarcinoma with synchronous bone metastasis.

作者信息

Xu Yao, Wu Haixiao, Wang Cong, Ma Yulin, Zhang Chao

机构信息

Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Tianjin, China.

The Sino-Russian Joint Research Center for Bone Metastasis in Malignant Tumor, Tianjin, China.

出版信息

Front Oncol. 2022 Oct 26;12:1045458. doi: 10.3389/fonc.2022.1045458. eCollection 2022.

DOI:10.3389/fonc.2022.1045458
PMID:36387155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9644070/
Abstract

Bone metastasis is one of the comorbidities of advanced lung cancer, eventually leading to an impaired quality of life. We present a case of a lung adenocarcinoma patient with synchronous bone metastasis. The patient possessed a superior survival time of more than five years under multidisciplinary treatment. Considering the balance of life expectancy and limb function, the metastatic site on the right humerus was successively surgically managed. Based on the present case, we emphasized the importance of treatment choice between anti-tumor and bone management in the long-term survival of cancer patients with synchronous bone metastasis.

摘要

骨转移是晚期肺癌的合并症之一,最终会导致生活质量受损。我们报告一例肺腺癌患者同时发生骨转移的病例。该患者在多学科治疗下存活时间超过五年。考虑到预期寿命和肢体功能的平衡,对右肱骨的转移部位先后进行了手术处理。基于本病例,我们强调了在同时发生骨转移的癌症患者长期生存中,抗肿瘤治疗与骨处理之间治疗选择的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bf3/9644070/48ec62550c33/fonc-12-1045458-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bf3/9644070/c920283ba52a/fonc-12-1045458-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bf3/9644070/890de4ab59fd/fonc-12-1045458-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bf3/9644070/48ec62550c33/fonc-12-1045458-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bf3/9644070/c920283ba52a/fonc-12-1045458-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bf3/9644070/890de4ab59fd/fonc-12-1045458-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bf3/9644070/48ec62550c33/fonc-12-1045458-g003.jpg

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The 100 most cited papers on bone metastasis: A bibliometric analysis.关于骨转移的100篇被引用次数最多的论文:一项文献计量分析。
J Bone Oncol. 2022 Jun 29;35:100443. doi: 10.1016/j.jbo.2022.100443. eCollection 2022 Aug.
2
Non-Small Cell Lung Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology.非小细胞肺癌,2022年第3版,美国国立综合癌症网络(NCCN)肿瘤学临床实践指南
J Natl Compr Canc Netw. 2022 May;20(5):497-530. doi: 10.6004/jnccn.2022.0025.
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Treatment of Advanced-Stage Non-Small Cell Lung Cancer.晚期非小细胞肺癌的治疗
Am J Respir Crit Care Med. 2022 Mar 1;205(5):P9-P10. doi: 10.1164/rccm.2055P9.
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Cancer statistics, 2022.癌症统计数据,2022 年。
CA Cancer J Clin. 2022 Jan;72(1):7-33. doi: 10.3322/caac.21708. Epub 2022 Jan 12.
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Predictive and Prognostic Biomarkers for Lung Cancer Bone Metastasis and Their Therapeutic Value.肺癌骨转移的预测和预后生物标志物及其治疗价值。
Front Oncol. 2021 Oct 14;11:692788. doi: 10.3389/fonc.2021.692788. eCollection 2021.
6
Common Pitfalls in the Management of Bone Metastasis of the Extremities - a Current Concept and Systematic Review of the Literature.四肢骨转移管理中的常见陷阱——当前概念和文献系统评价。
Anticancer Res. 2021 Oct;41(10):4665-4672. doi: 10.21873/anticanres.15280.
7
The emergence of new prognostic scores in lung cancer patients with spinal metastasis: A 12-year single-center retrospective study.肺癌脊柱转移患者新预后评分的出现:一项为期12年的单中心回顾性研究。
J Cancer. 2021 Jul 25;12(18):5644-5653. doi: 10.7150/jca.60821. eCollection 2021.
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Sites of Synchronous Distant Metastases, Prognosis, and Nomogram for Small Cell Lung Cancer Patients with Bone Metastasis: A Large Cohort Retrospective Study.小细胞肺癌骨转移患者的同步远处转移部位、预后及列线图:一项大型队列回顾性研究
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NCCN Guidelines® Insights: Palliative Care, Version 2.2021.NCCN 指南®洞察:姑息治疗,第 2.2021 版。
J Natl Compr Canc Netw. 2021 Jul 28;19(7):780-788. doi: 10.6004/jnccn.2021.0033.
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