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关于颈椎放疗中颈动脉剂量的考量

Considerations regarding carotid artery dose in radiotherapy of the cervical spine.

作者信息

Nieder Carsten, Grant David McKenzie

机构信息

Department of Oncology and Palliative Medicine, Nordland Hospital, Bodø, Norway.

Department of Clinical Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.

出版信息

Clin Transl Radiat Oncol. 2022 Nov 8;38:77-80. doi: 10.1016/j.ctro.2022.11.002. eCollection 2023 Jan.

DOI:10.1016/j.ctro.2022.11.002
PMID:36388246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9664353/
Abstract

Radiation to the carotid arteries, e.g. in the context of head and neck cancer treatment, is one of several risk factors for artery stenosis. In principle, this fact may also have implications for stereotactic cervical spine radiotherapy, because long-term survival can be achieved in patients with oligometastatic disease and favorable prognostic features. Here, we suggest that radiation dose distributions with reduced dose to the carotid artery are achievable when planning stereotactic cervical spine radiotherapy. Patients with high likelihood of long-term survival may benefit from such vessel-sparing approaches.

摘要

例如在头颈部癌症治疗中,对颈动脉进行放疗是动脉狭窄的几个危险因素之一。原则上,这一事实可能也适用于立体定向颈椎放疗,因为寡转移疾病且具有良好预后特征的患者可实现长期生存。在此,我们认为在计划立体定向颈椎放疗时,可实现减少对颈动脉剂量的放射剂量分布。具有高长期生存可能性的患者可能会从这种血管保护方法中获益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba11/9664353/e16ca5dd0f9d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba11/9664353/6f03182900ad/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba11/9664353/e16ca5dd0f9d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba11/9664353/6f03182900ad/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba11/9664353/e16ca5dd0f9d/gr2.jpg

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2
Dose-Volume Comparison of IMRT and PSPT Treatment Plans for Early-Stage Glottic Cancer.早期声门癌调强放射治疗(IMRT)与质子束扫描调强放疗(PSPT)治疗计划的剂量-体积比较
Int J Part Ther. 2020 Nov 23;7(2):42-50. doi: 10.14338/IJPT-20-00008.1. eCollection 2020 Fall.
3
A systematic review and practical considerations of stereotactic body radiotherapy in the treatment of head and neck cancer.
立体定向体部放疗治疗头颈部癌症的系统评价及实际考虑
Br J Radiol. 2021 Jan 1;94(1117):20200332. doi: 10.1259/bjr.20200332. Epub 2020 Sep 24.
4
Outcome and toxicity of hypofractionated image-guided SABR for spinal oligometastases.影像引导下大分割立体定向体部放疗治疗脊柱寡转移瘤的疗效与毒性
Clin Transl Radiat Oncol. 2020 Jun 25;24:65-70. doi: 10.1016/j.ctro.2020.06.011. eCollection 2020 Sep.
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Evolving Role of Stereotactic Body Radiation Therapy in the Management of Spine Metastases: Defining Dose and Dose Constraints.立体定向体部放射治疗在脊柱转移瘤治疗中的作用演变:定义剂量和剂量限制。
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