Malik Tom, Wheeler Robert, Hall Nigel J, Gray Juliet
Department of Paediatric Surgery and Urology, Southampton Children's Hospital, Southampton, United Kingdom.
Department of Paediatric Surgery, Southampton Children's Hospital, Southampton, United Kingdom.
European J Pediatr Surg Rep. 2022 Nov 11;10(1):e148-e151. doi: 10.1055/a-1926-2053. eCollection 2022 Jan.
Mature ovarian teratoma has the potential to occur metachronously in the contralateral ovary. There are significant implications for fertility as bilateral oophorectomy may be indicated. In prepubertal girls, ovarian tissue cryopreservation (OTC) offers the only possibility of a future biological pregnancy but outcome data are limited. We present a case of prepubertal OTC in a 12-year-old girl undergoing a second oophorectomy for metachronous contralateral mature teratoma. We offer a discussion of the challenges that emerged regarding perioperative decision-making, balancing the need for safe oncological resection with the desire to preserve fertility.
成熟卵巢畸胎瘤有可能在对侧卵巢异时发生。由于可能需要进行双侧卵巢切除术,这对生育能力有重大影响。在青春期前女孩中,卵巢组织冷冻保存(OTC)是未来实现自然妊娠的唯一可能方法,但相关结果数据有限。我们报告了一例12岁青春期前女孩的OTC病例,该女孩因异时性对侧成熟畸胎瘤接受第二次卵巢切除术。我们讨论了围手术期决策中出现的挑战,即在安全的肿瘤切除需求与保留生育能力的愿望之间取得平衡。