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用于预防飞沫和气溶胶传播的负压空气传播感染隔离罩单元的功能分析——一项实验研究。

Functional analysis of a negative pressure airborne infection isolation canopy unit for the prevention of transmission of droplets and aerosols- An experimental study.

作者信息

Paul Shamik K, Suryavanshi Ajay V, Parate Kiran D, Samgiskar Prasad T

机构信息

Department of Anaesthesiology and Critical Care, Armed Forces Medical College, Pune, India.

Principal Engineer, Nayam Innovations Pvt. Ltd., Pune, Maharashtra, India.

出版信息

Indian J Anaesth. 2022 Sep;66(9):657-664. doi: 10.4103/ija.ija_309_22. Epub 2022 Sep 20.

DOI:10.4103/ija.ija_309_22
PMID:36388448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9662089/
Abstract

BACKGROUND AND AIMS

This study describes the functional analysis of a negative pressure canopy unit developed to reduce infective aerosol and droplet spread in ad-hoc wards created to handle patients suffering from infective respiratory illnesses such as those recently encountered in the COVID-19 pandemic.

METHODS

An experimental study was conducted to verify the functional analysis of a canopy unit for the following variables: a) Quantitative and qualitative analysis of aerosol generation, b) Efficacy of canopy as containment device and c) Aerosol clearance from canopy over a period. We describe the process in the form of a problem statement, a discussion of design considerations (including Computer Aided Design modelling and a functional analysis of the system using a variety of simulated conditions which included various experiments for the purpose of testing the safety and efficiency of the system. We also incorporated Computational Fluid Dynamics analyses to assist us in design modifications of the unit using Euler-Lagrange approach for aerosol tracking.

RESULTS

As demonstrated by the series of experiments, it was seen that the aerosol load under the testing conditions reduced significantly. The canopy unit restricted the aerosol particles which either got adhered to the canopy walls or went into recirculation inside the canopy. In experimental conditions, the fan-filter unit was able to operate at >95% efficiency.

CONCLUSION

This device exhibited 95-99% efficiency in eliminating aerosols which would reduce the exposure of health care workers to infective aerosols, which is not only specific to severe acute respiratory syndrome coronavirus (SARS-CoV)-2, but also to other airborne transmitted diseases.

摘要

背景与目的

本研究描述了一种负压罩单元的功能分析,该单元旨在减少在为治疗感染性呼吸道疾病患者而临时设立的病房中感染性气溶胶和飞沫的传播,这些疾病如最近在新冠疫情中出现的疾病。

方法

进行了一项实验研究,以验证罩单元在以下变量方面的功能分析:a)气溶胶生成的定量和定性分析,b)罩作为隔离装置的功效,c)一段时间内罩内气溶胶的清除情况。我们以问题陈述的形式描述该过程,讨论设计考虑因素(包括计算机辅助设计建模以及使用各种模拟条件对系统进行功能分析,这些模拟条件包括各种用于测试系统安全性和效率的实验。我们还纳入了计算流体动力学分析,以帮助我们使用欧拉-拉格朗日方法进行气溶胶跟踪来对单元进行设计修改。

结果

通过一系列实验表明,在测试条件下气溶胶负荷显著降低。罩单元限制了气溶胶颗粒,这些颗粒要么附着在罩壁上,要么在罩内进入再循环。在实验条件下,风扇过滤单元能够以>95%的效率运行。

结论

该装置在消除气溶胶方面表现出95 - 99%的效率,这将减少医护人员接触感染性气溶胶的机会,这不仅适用于严重急性呼吸综合征冠状病毒(SARS)-2,也适用于其他空气传播疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/cf0f245e6a09/IJA-66-657-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/ce9b0cde74d4/IJA-66-657-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/6d2f5c905ffa/IJA-66-657-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/bd3500876e31/IJA-66-657-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/d77b6ae3692a/IJA-66-657-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/cf0f245e6a09/IJA-66-657-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/ce9b0cde74d4/IJA-66-657-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/6d2f5c905ffa/IJA-66-657-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/bd3500876e31/IJA-66-657-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/d77b6ae3692a/IJA-66-657-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3630/9662089/cf0f245e6a09/IJA-66-657-g005.jpg

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