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左心耳封堵术后大量与器械相关的血栓形成：术中对机制的见解

Massive Device-Related Thrombus After LAA Occlusion: Intraoperative Insights Into Mechanism.

作者信息

Vukomanovic Damir, Unzek Samuel, Malik Kashif, Taase Alicia, Zawaneh Michael, Weiss Peter, Fang Kenith, Tung Roderick

机构信息

Department of Internal Medicine, University of Arizona College of Medicine, Banner University Medical Center-Phoenix, Phoenix, Arizona, USA.

Division of Cardiology, University of Arizona College of Medicine, Banner University Medical Center-Phoenix, Phoenix, Arizona, USA.

出版信息

JACC Case Rep. 2022 Nov 2;4(21):1409-1413. doi: 10.1016/j.jaccas.2022.07.037.

DOI:10.1016/j.jaccas.2022.07.037
PMID:36388709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9664007/
Abstract

In patients with a contraindication to oral anticoagulation, the left atrial appendage occlusion devices are an approved alternative. Device-related thrombus is a recognized complication, but underlying mechanisms are incompletely understood. In this case series, the authors describe potentially the same mechanism of thrombosis with intraoperative images of incomplete endothelialization. ().

摘要

对于有口服抗凝禁忌的患者，左心耳封堵装置是一种已获批准的替代方案。装置相关血栓形成是一种公认的并发症，但其潜在机制尚未完全明确。在本病例系列中，作者通过术中不完全内皮化的图像描述了可能相同的血栓形成机制。（）

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a015/9664007/b20a250b359e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a015/9664007/e73e6335be08/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a015/9664007/481f8898355e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a015/9664007/80f732d1de85/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a015/9664007/b20a250b359e/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a015/9664007/e73e6335be08/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a015/9664007/481f8898355e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a015/9664007/80f732d1de85/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a015/9664007/b20a250b359e/gr3.jpg

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JACC Clin Electrophysiol. 2021 Dec;7(12):1533-1543. doi: 10.1016/j.jacep.2021.04.012. Epub 2021 Jun 30.
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Antithrombotic Therapy and Device-Related Thrombosis Following Endovascular Left Atrial Appendage Closure.经血管左心耳封堵术后的抗血栓治疗与器械相关血栓形成。
JACC Cardiovasc Interv. 2019 Jun 10;12(11):1067-1076. doi: 10.1016/j.jcin.2018.11.001. Epub 2019 May 15.
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Left Atrial Appendage Closure: Two Steps Forward, One Step Back.
J Am Heart Assoc. 2024 Jan 2;13(1):e030080. doi: 10.1161/JAHA.123.030080. Epub 2023 Dec 29.
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Acute Formation of Thrombus on a Left Atrial Appendage Occlusion Device Immediately After Detachment.左心耳封堵装置脱离后立即形成急性血栓。
JACC Case Rep. 2023 Jun 23;19:101933. doi: 10.1016/j.jaccas.2023.101933. eCollection 2023 Aug 2.
左心耳封堵术：前进两步，后退一步。
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4
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