Alramadhan Saja A, Ruddocks Lauren A, Bhattacharyya Indraneel, Cohen Donald M, Islam Mohammed N
Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry, Gainesville, FL, USA.
Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry, Gainesville, FL, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2023 Jan;135(1):e10-e13. doi: 10.1016/j.oooo.2022.08.015. Epub 2022 Sep 7.
Adenoid ameloblastoma with dentinoid (AAD) is an extremely rare central neoplasm of the gnathic bones with no reported case of peripheral AAD. Adenoid ameloblastoma with dentinoid was first reported by Slabbert et al. in 1992 under the term "dentinoameloblastoma." However, the Armed Forces Institute of Pathology introduced the name "adenoid ameloblastoma with dentinoid" in 1994. Histologically, AAD shows features of ameloblastoma and adenomatoid odontogenic tumor along with a calcified product resembling dentin. The biological behavior of central AAD is not well established, though, in the literature, several reports consider it to be among the more aggressive odontogenic neoplasms, with a propensity for local invasion and recurrence. The demographic characteristics, clinical features, behavior, and prognosis of the peripheral AAD (PAAD) are unknown. To the best of our knowledge, this is the first reported case of PAAD in a 62-year-old woman.
伴牙本质样结构的腺样成釉细胞瘤(AAD)是一种极其罕见的颌骨中心性肿瘤,目前尚无外周型AAD的病例报道。伴牙本质样结构的腺样成釉细胞瘤最早由斯拉伯特等人于1992年以“牙本质成釉细胞瘤”之名报道。然而,美国武装部队病理研究所于1994年引入了“伴牙本质样结构的腺样成釉细胞瘤”这一名称。组织学上,AAD表现出成釉细胞瘤和腺样牙源性肿瘤的特征,同时伴有类似牙本质的钙化产物。尽管文献中一些报道认为中心型AAD是侵袭性较强的牙源性肿瘤之一,具有局部侵袭和复发倾向,但其生物学行为尚未完全明确。外周型AAD(PAAD)的人口统计学特征、临床特点、行为及预后均不明确。据我们所知,本文报道的是首例62岁女性外周型AAD病例。