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伴有牙本质样结构和细胞异型性的腺样成釉细胞瘤:1例报告及文献复习

Adenoid ameloblastoma with dentinoid and cellular atypia: a case report and literature review.

作者信息

Khalele B Ae O

机构信息

Department of Diagnostic Pathology, Ministry of Health, Egypt.

出版信息

Pathologica. 2017 Dec;109(4):379-381.

Abstract

Adenomatoid odontogenic tumor (AOT) is always benign. Given the very rare recurrence rate and the zero potential of malignant transformation, authors have considered it a hamartoma. Accordingly, 'AOT' is no more than a misnomer. This report, however, describes the first recognition of cellular atypia and plemorphism in a peripheral orophayrngeal AOT which embraces an ameloblastic component. The overall picture was diagnosed, after careful histological and immunohitochemical assessment, as a peripheral adenoid ameloblastoma. This find may promote a new pathogenetic scenario to the nosology of this debatable lesion.

摘要

腺牙源性肿瘤(AOT)通常为良性。鉴于其极低的复发率和零恶变潜能,作者们曾认为它是一种错构瘤。因此,“AOT”不过是一个误称。然而,本报告描述了首例在外周口咽AOT中识别出细胞异型性和多形性,该AOT包含成釉细胞成分。经过仔细的组织学和免疫组织化学评估后,整体诊断为外周腺样成釉细胞瘤。这一发现可能会为这种有争议病变的分类学带来新的发病机制设想。

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