Department of Oral Pathology and Microbiology, Government Dental College and Hospital, Mumbai, India.
Sultan Qaboos Univ Med J. 2022 Aug;22(3):325-338. doi: 10.18295/squmj.9.2021.127. Epub 2022 Aug 25.
This article aimed to collectively present the demographic, clinical, radiographic and histopathological features as well as the treatment performed along with its outcome for all the cases of adenoid ameloblastoma with dentinoid (AAD) reported in scientific literature till date. Ameloblastoma and adenomatoid odontogenic tumours are the most common odontogenic neoplasms. However, AAD, a hybrid variant of the two lesions, is found to be extremely rare. The lesion comprises of characteristic histopathological features of ameloblastoma and adenomatoid odontogenic tumour and shares certain clinical characteristics with either of the entities. AAD may be considered to be present at the more aggressive end of spectrum of benign odontogenic neoplasms. Owing to the frequent tendency of the lesions to be underdiagnosed, careful histopathological screening of submitted biopsies is warranted. With the increase in number of reported cases in the recent years, it is likely to be included as a separate entity in the upcoming World Health Organization classification.
本文旨在汇总迄今为止在科学文献中报道的所有牙源性腺样瘤伴牙本质型(AAD)病例的人口统计学、临床、影像学和组织病理学特征以及所进行的治疗及其结果。成釉细胞瘤和腺牙源性肿瘤是最常见的牙源性肿瘤。然而,AAD 是这两种病变的混合变体,极为罕见。该病变具有成釉细胞瘤和腺牙源性肿瘤的特征性组织病理学特征,并与这两种病变中的任何一种具有某些临床特征。AAD 可能被认为是良性牙源性肿瘤谱中更具侵袭性的一端。由于病变经常被误诊,因此有必要对送检的活检进行仔细的组织病理学筛查。近年来,随着报道病例数量的增加,它很可能被纳入即将发布的世界卫生组织分类中的一个单独实体。