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猴痘的实验室诊断:临床实践及需要认识的要点。

Laboratory Diagnosis for Monkeypox: Clinical Practice and Important Points to Be Recognized.

机构信息

Private Academic Consultant, Bangkok, Thailand.

Joseph Ayobabalola University, Ikeji-Arakeji, Nigeria.

出版信息

Adv Exp Med Biol. 2023;1410:13-20. doi: 10.1007/5584_2022_741.

Abstract

Monkeypox is a unique variety of pox infection. WHO has already acknowledged the seriousness of the large monkeypox outbreak in 2022. The disease commonly presents as acute febrile illness with skin lesion. However, a fever or a skin lesion, however, is sometimes not detectable. Without the peculiar appearance, the physician might have missed the problem and made a false diagnosis. Basically, the clinical diagnosis is the simplest procedure and must be used by practitioners. Laboratory methods can help confirm diagnosis. The gold standard for diagnosis is the molecular-based diagnosis. There are also other available approaches such as point of care testing. In this article, we also summarize and discuss important practical points in laboratory diagnosis for monkeypox.

摘要

猴痘是一种独特的痘病毒感染。世界卫生组织已经认识到 2022 年大规模猴痘爆发的严重性。这种疾病通常表现为急性发热性疾病伴皮肤损伤。然而,有时可能检测不到发热或皮肤损伤。如果没有特殊的表现,医生可能会忽略这个问题,导致误诊。基本上,临床诊断是最简单的程序,必须由从业者使用。实验室方法可以帮助确认诊断。诊断的金标准是基于分子的诊断。还有其他可用的方法,如即时检测。本文还总结和讨论了猴痘实验室诊断的重要实用要点。

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