电针对强直性脊柱炎的有效性和安全性的系统评价和荟萃分析方案。
Effectiveness and safety of electroacupuncture for ankylosing spondylitis: A protocol for a systematic reviews and meta-analysis.
机构信息
Jiujiang First People's Hospital Rheumatology Department, Jiujiang, Jiangxi, China.
出版信息
Medicine (Baltimore). 2022 Nov 11;101(45):e31706. doi: 10.1097/MD.0000000000031706.
INTRODUCTION
Ankylosing spondylitis (AS) is a type of autoimmune disease commonly characterized by joint pain and stiffness. This disease progression can exhibit common deformities and other activities with limited symptoms and significantly impacts people's work and life. Electroacupuncture (EA) as a traditional Chinese therapy, showing several advantages (e.g., safety, economy, and less side effects), has been extensively used to treat AS. However, its curative effect is supported by limited evidence. Accordingly, the present study aims to comprehensively assess the reliability of EA in AS treatment.
METHODS AND ANALYSIS
The study will conduct a systematic review and meta-analysis. Seven databases, including the Embase, Cochrane Library, Pubmed, SinoMed, CNKI, VIP, and Wanfang Data, will be searched using predefined search terms to identify relevant studies. The primary outcomes will be the clinical efficiency, the Bath AS Disease Activity Index, and the Visual Analog Scale. Eligible studies should report at least 1 of these primary outcomes. Eligible studies designed as randomized controlled trials will be included for meta-analysis, while other related clinical studies will be reviewed. The methodological quality of the included studies will be assessed with a previously established checklist. The Cochrane Collaboration's bias risk tool will be used for assessing the bias of included randomized controlled trials. Stata 17.0 software is used for meta-analysis.
RESULTS
The protocol will be used to assess the efficacy and safety of EA in AS treatment.
CONCLUSION
This review reliably evidences whether EA is a reliable method for the intervention of AS.
简介
强直性脊柱炎（AS）是一种常见的自身免疫性疾病，通常表现为关节疼痛和僵硬。这种疾病的进展会导致常见的畸形和其他活动受限，对人们的工作和生活有显著影响。电针（EA）作为一种传统的中医疗法，具有安全性高、经济实惠、副作用少等优点，已广泛用于治疗 AS。然而，其疗效的证据有限。因此，本研究旨在全面评估 EA 在 AS 治疗中的可靠性。
方法和分析
本研究将进行系统评价和荟萃分析。将使用预先设定的检索词，在七个数据库（Embase、Cochrane 图书馆、PubMed、SinoMed、CNKI、VIP 和万方数据）中搜索相关研究。主要结局指标将是临床疗效、Bath AS 疾病活动指数和视觉模拟评分。合格的研究应至少报告其中 1 个主要结局指标。合格的研究设计为随机对照试验将进行荟萃分析，而其他相关的临床研究将进行综述。将使用先前建立的检查表评估纳入研究的方法学质量。将使用 Cochrane 协作偏倚风险工具评估纳入的随机对照试验的偏倚。Stata 17.0 软件将用于荟萃分析。
结果
该方案将用于评估 EA 在 AS 治疗中的疗效和安全性。
结论
本综述可靠地证明了 EA 是否是治疗 AS 的可靠方法。
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