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用于强直性脊柱炎的中药阳和汤:系统评价与Meta分析方案

Chinese herbal medicine Yanghe decoction for ankylosing spondylitis: A protocol for systematic review and meta-analysis.

作者信息

Xu Xiaosheng, Chen Hong, Yuan Xiaoping, Wan Yi, Gong Liangjin, Ma Zeren, Xu Tao

机构信息

Nanchang Hongdu Hospital of Traditional Chinese Medicine, Nanchang.

Gongqingcheng People's Hospital, Gongqingcheng, China.

出版信息

Medicine (Baltimore). 2020 Nov 25;99(48):e23466. doi: 10.1097/MD.0000000000023466.

Abstract

BACKGROUND

Chinese herbal medicine is a commonly used traditional treatment for ankylosing spondylitis (AS). Among them, Yanghe decoction (YHD) has an obvious effect in relieving the symptoms of AS, but its efficacy is still controversial. The purpose of this study is to systematically evaluate the effectiveness and safety of YHD in the treatment of AS patients.

METHODS

From the establishment to September 2020, we will search a total of 7 electronic databases including PubMed, Cochrane Library, Embase, CNKI, VIP, WanFang, and the Chinese SinoMed Database. Two independent reviewers will search the database for relevant randomized controlled trials (RCTs), extract data, and evaluate the quality of the included RCTs. Data analysis will be processed by RevMan V.5.4 software.

RESULTS

The results of this systematic review will be published in a peer-reviewed journal.

CONCLUSION

This study will provide evidence for the effectiveness of YHD in treating patients with AS.

摘要

背景

中药是强直性脊柱炎(AS)常用的传统治疗方法。其中,阳和汤(YHD)在缓解AS症状方面有明显效果,但其疗效仍存在争议。本研究的目的是系统评价阳和汤治疗AS患者的有效性和安全性。

方法

从建库至2020年9月,我们将共检索7个电子数据库,包括PubMed、Cochrane图书馆、Embase、中国知网(CNKI)、维普资讯(VIP)、万方数据库以及中国生物医学文献数据库(SinoMed)。两名独立的评价员将检索数据库以查找相关的随机对照试验(RCT),提取数据并评估纳入的RCT的质量。数据分析将采用RevMan V.5.4软件进行处理。

结果

本系统评价的结果将发表在同行评审期刊上。

结论

本研究将为阳和汤治疗AS患者的有效性提供证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38e9/7710208/3904f7893270/medi-99-e23466-g001.jpg

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