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结核病与呼吸疾病机构中老年人结核病的临床谱

Clinical spectrum of TB in elderly in a TB & respiratory institution.

作者信息

Singla Rupak, Gupta Amitesh, Bhattacherjee Nilotpal, Choudhary Madhumita Paul

机构信息

Department of Tuberculosis and Chest Diseases, National Institute of Tuberculosis and Respiratory Diseases, New Delhi, 110030, India.

Department of Respiratory Medicine, Maulana Azad Medical College and Associated Lok Nayak Hospital, New Delhi, 110002, India.

出版信息

Indian J Tuberc. 2022;69 Suppl 2:S220-S224. doi: 10.1016/j.ijtb.2022.10.007. Epub 2022 Oct 26.

DOI:10.1016/j.ijtb.2022.10.007
PMID:36400513
Abstract

Tuberculosis has maximum burden among young population in developing countries like India. However, children and elderly form a special group where TB may have atypical presentation. This presents with epidemiological, diagnostic and treatment challenges in these groups which may need special attention in the national programmes for TB. Due to atypical presentation, elderly population is vulnerable to frequent misdiagnosis and disease may already be in advanced stage when correct diagnosis is made. Not only this, adjustment of drug dosages and high chances of adverse drug reaction make the management of TB more complicated in elderly. Mortality due to TB is also higher in this group as compared to young patients of TB. This view point briefly highlights the epidemiological, clinical and disease outcome aspects of TB disease in elderly patients.

摘要

在印度等发展中国家,结核病在年轻人群体中的负担最为沉重。然而,儿童和老年人构成了一个特殊群体,结核病在他们身上可能有非典型表现。这给这些群体带来了流行病学、诊断和治疗方面的挑战,而这些挑战在国家结核病防治计划中可能需要特别关注。由于表现不典型,老年人群体容易频繁被误诊,在做出正确诊断时疾病可能已经处于晚期。不仅如此,药物剂量的调整以及药物不良反应的高发生率使得老年结核病的管理更加复杂。与年轻结核病患者相比,该群体因结核病导致的死亡率也更高。本文观点简要强调了老年结核病患者结核病的流行病学、临床和疾病转归方面情况。

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