Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Anhui Provincial Laboratory of Inflammatory and Immune Diseases, Hefei, Anhui, China.
Hospital-Acquired Infection Control Department, The First Hospital of Jiaxing & The Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.
Sci Total Environ. 2023 Feb 10;859(Pt 1):160244. doi: 10.1016/j.scitotenv.2022.160244. Epub 2022 Nov 17.
The relationship between greenness and health emerges as new public health concern. More published studies from multiple areas have explored the relationship between greenness and allergic rhinitis (AR) in children and adolescents. This study aims to determine the association between greenness and allergic rhinitis by systematic review and meta-analysis, in order to provide a more comprehensive assessment of the impact of greenness on AR in children and adolescents.
The relative literature was systematically searched in PubMed, Embase, and Web of science lastly on September 25, 2022. Terms related to greenness and allergic rhinitis were used for searching. Summary effect estimates of greenness on AR in children and adolescents were calculated for per 10 % increase of greenness exposure with different buffer sizes by random-effects model.
A total of 579 studies were screened, and fourteen studies from Europe, Asia and North America were finally included. Most greenness exposure were measured by normalized difference vegetation index (NDVI). Enhanced vegetation index, outdoor-green environmental score and existed to measuring different greenness types. Greenness surrounding residences and schools were assessed. The overall effect of greenness on primary outcome was 1.00 (95%CI = 0.99-1.00). Most effect estimates of greenness were included in the NDVI-500 m group, and the pooled OR was 0.99 (95%CI = 0.97-1.01). No significant pooled estimates were found in analyses with study locations.
This study indicates no significant association between greenness exposure and AR in children and adolescents. Various exposure measures and conversion of data may affect the results of this meta-analysis. More precise assessment of personal greenness exposure in well-designed prospective studies are vital for drawing a definite association in future. Furthermore, greenness exposure surrounding schools should be paid considerable attention for its effect on AR in school-aged children and adolescents.
绿色环境与健康之间的关系成为新的公共卫生关注点。越来越多来自不同领域的已发表研究探讨了绿色环境与儿童和青少年变应性鼻炎（AR）之间的关系。本研究旨在通过系统评价和荟萃分析来确定绿色环境与变应性鼻炎之间的关系，以便更全面地评估绿色环境对儿童和青少年 AR 的影响。
最后于 2022 年 9 月 25 日在 PubMed、Embase 和 Web of Science 中系统检索了相关文献。使用与绿色环境和变应性鼻炎相关的术语进行检索。采用随机效应模型，计算不同缓冲区大小下，绿色环境每增加 10%时对儿童和青少年变应性鼻炎的综合效应估计值。
共筛选出 579 篇研究，最终纳入来自欧洲、亚洲和北美的 14 项研究。大多数绿色环境暴露的测量指标是归一化差异植被指数（NDVI）。增强植被指数、户外绿色环境评分和已有的多种绿色环境类型的测量方法也被使用。对居住和学校周围的绿色环境进行了评估。绿色环境对主要结局的总体效应为 1.00（95%CI=0.99-1.00）。大多数绿色环境的效应估计值包含在 NDVI-500m 组中，汇总 OR 为 0.99（95%CI=0.97-1.01）。在按研究地点进行的分析中，未发现显著的汇总估计值。
本研究表明，儿童和青少年的绿色环境暴露与 AR 之间无显著关联。不同的暴露测量方法和数据转换可能会影响本荟萃分析的结果。未来需要在设计良好的前瞻性研究中更精确地评估个人的绿色环境暴露，以确定明确的关联。此外，应特别关注学校周围的绿色环境暴露，因为其对学龄儿童和青少年的 AR 有影响。
