Bass Gary Alan, Duffy Caoimhe C, Kaplan Lewis J, Sarani Babak, Martin Niels D, Ismail Ahmad Mohammad, Cao Yang, Forssten Maximilian Peter, Mohseni Shahin
Division of Traumatology, Surgical Critical Care and Emergency Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA; School of Medical Sciences, Orebro University, Orebro, Sweden; Leonard Davis Institute of Health Economics (LDI), University of Pennsylvania, Philadelphia, USA; Center for Peri-Operative Outcomes Research and Transformation (CPORT), University of Pennsylvania, Philadelphia, USA.
Leonard Davis Institute of Health Economics (LDI), University of Pennsylvania, Philadelphia, USA; Center for Peri-Operative Outcomes Research and Transformation (CPORT), University of Pennsylvania, Philadelphia, USA.
Injury. 2023 Jan;54(1):56-62. doi: 10.1016/j.injury.2022.11.039. Epub 2022 Nov 13.
Risk factors for mortality and in-hospital morbidity among geriatric patients with traumatic rib fractures remain unclear. Such patients are often frail and demonstrate a high comorbidity burden. Moreover, outcomes anticipated by current rubrics may reflect the influence of multisystem injury or surgery, and thus not apply to isolated injuries in geriatric patients. We hypothesized that the Revised Cardiac Risk Index (RCRI) may assist in risk-stratifying geriatric patients following rib fracture.
All geriatric patients (age ≥65 years) with a conservatively managed rib fracture owing to an isolated thoracic injury (thorax AIS ≥1), in the 2013-2019 TQIP database were assessed including demographics and outcomes. The association between the RCRI and in-hospital morbidity as well as mortality was analyzed using Poisson regression models while adjusting for potential confounders.
96,750 geriatric patients sustained rib fractures. Compared to those with RCRI 0, patients with an RCRI score of 1 had a 16% increased risk of in-hospital mortality [adjusted incidence rate ratio (adj-IRR), 95% confidence interval (CI): 1.16 (1.02-1.32), p=0.020]. An RCRI score of 2 [adj-IRR (95% CI): 1.72 (1.44-2.06), p<0.001] or ≥3 [adj-IRR (95% CI): 3.07 (2.31-4.09), p<0.001] was associated with an even greater mortality risk. Those with an increased RCRI also exhibited a higher incidence of myocardial infarction, cardiac arrest, stroke, and acute respiratory distress syndrome.
Geriatric patients with rib fractures and an RCRI ≥1 represent a vulnerable and high-risk group. This index may inform the decision to admit for inpatient care and can also guide patient and family counseling as well as computer-based decision-support.
老年创伤性肋骨骨折患者的死亡率及院内发病率的危险因素仍不明确。这类患者通常身体虚弱,合并症负担较重。此外,当前评分标准所预期的结果可能反映了多系统损伤或手术的影响,因此并不适用于老年患者的单纯损伤情况。我们推测,修订后的心脏风险指数(RCRI)可能有助于对肋骨骨折后的老年患者进行风险分层。
对2013 - 2019年TQIP数据库中所有因单纯胸部损伤(胸部损伤严重程度评分[AIS]≥1)而接受保守治疗的肋骨骨折老年患者(年龄≥65岁)进行评估,包括人口统计学资料和治疗结果。使用泊松回归模型分析RCRI与院内发病率及死亡率之间的关联,并对潜在混杂因素进行校正。
96,750例老年患者发生肋骨骨折。与RCRI为0的患者相比,RCRI评分为1的患者院内死亡风险增加16%[校正发病率比(adj - IRR),95%置信区间(CI):1.16(1.02 - 1.32);p = 0.020]。RCRI评分为2[adj - IRR(95%CI):1.72(1.44 - 2.06);p < 0.001]或≥3[adj - IRR(95%CI):3.07(2.31 - 4.09);p < 0.001]与更高的死亡风险相关。RCRI升高的患者还表现出更高的心肌梗死、心脏骤停、中风及急性呼吸窘迫综合征发生率。
RCRI≥1的老年肋骨骨折患者是一个脆弱的高危群体。该指数可为住院治疗的决策提供参考,还可指导患者及家属咨询以及基于计算机的决策支持。