Hainan University-HSF/LWL Collaborative Innovation Laboratory, School of Food Science and Engineering, Hainan University, 58 People Road, Haikou 570228, PR China; SCUT-Zhuhai Institute of Modern Industrial Innovation, School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou 510640, PR China.
School of Food Science and Technology, Guangdong Ocean University, Yangjiang 529500, Guangdong, PR China.
Adv Colloid Interface Sci. 2023 Jan;311:102813. doi: 10.1016/j.cis.2022.102813. Epub 2022 Nov 15.
Emulsions are multiscale and thermodynamically unstable systems which will undergo various unstable processes over time. The behavior of emulsifier molecules at the oil-water interface and the properties of the interfacial film are very important to the stability of the emulsion. In this paper, we mainly discussed the instability phenomena and mechanisms of emulsions, the effects of interfacial films on the long-term stability of emulsions and summarized a set of systematic multiscale combined methods for studying emulsion stability, including droplet size and distribution, zeta-potential, the continuous phase viscosity, adsorption mass and thickness of the interfacial film, interfacial dilatational rheology, interfacial shear rheology, particle tracking microrheology, visualization technologies of the interfacial film, molecular dynamics simulation and the quantitative evaluation methods of emulsion stability. This review provides the latest research progress and a set of systematic multiscale combined techniques and methods for researchers who are committed to the study of oil-water interface and emulsion stability. In addition, this review has important guiding significances for designing and customizing interfacial films with different properties, so as to obtain emulsion-based delivery systems with varying stability, oil digestibility and bioactive substance utilization.
乳液是多尺度和热力学不稳定的体系，随着时间的推移会经历各种不稳定过程。乳化剂分子在油水界面上的行为和界面膜的性质对乳液的稳定性非常重要。本文主要讨论了乳液的不稳定性现象和机制，界面膜对乳液长期稳定性的影响，并总结了一套系统的多尺度组合方法来研究乳液稳定性，包括液滴大小和分布、Zeta 电位、连续相粘度、界面膜的吸附质量和厚度、界面扩张流变学、界面剪切流变学、粒子跟踪微流变学、界面膜可视化技术、分子动力学模拟和乳液稳定性的定量评价方法。本综述为致力于油水界面和乳液稳定性研究的研究人员提供了最新的研究进展和一套系统的多尺度组合技术和方法。此外，本综述对设计和定制具有不同性质的界面膜具有重要的指导意义，从而获得具有不同稳定性、油消化率和生物活性物质利用率的基于乳液的递药系统。
