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韩国孕妇对无创产前检测的知情选择:一项横断面研究。

Informed choice of pregnant women regarding noninvasive prenatal testing in Korea: a cross-sectional study.

作者信息

Choi Hyunkyung

机构信息

College of Nursing and Research Institute of Nursing Science, Kyungpook National University, Daegu, KoreaCollege of Nursing and Research Institute of Nursing Science, Kyungpook National University, Daegu, Korea.

出版信息

Korean J Women Health Nurs. 2022 Sep;28(3):235-249. doi: 10.4069/kjwhn.2022.09.10. Epub 2022 Sep 30.

DOI:10.4069/kjwhn.2022.09.10
PMID:36403575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9619159/
Abstract

PURPOSE

This study explored the degree to which pregnant women in Korea made informed choices regarding noninvasive prenatal testing (NIPT) and investigated factors influencing whether they made informed choices.

METHODS

In total, 129 pregnant women in Korea participated in a web-based survey. Multidimensional measures of informed choice regarding NIPT and decisional conflict were used to measure participants' levels of knowledge, attitudes, deliberation, uptake, and decisional conflict related to NIPT. Additional questions were asked about participants' NIPT experiences and opinions.

RESULTS

All 129 pregnant women were recruited from an online community. Excluding those who expressed neutral attitudes toward NIPT, according to the definition of informed choice used in this study, only 91 made an informed choice (n=63, 69.2%) or an uninformed choice (n=28, 30.8%). Of the latter, 75.0% had insufficient knowledge, 39.3% made a value-inconsistent decision, and 14.3% did not deliberate sufficiently. No difference in decisional conflict was found between the two groups. A significant difference was found between the two groups in the reasons why NIPT was introduced or recommended (p=.021). Multiple logistic regression analysis showed that pregnant women who were knowledgeable (odds ratio [OR], 4.77; 95% confidence interval [CI], 2.17- 10.47) and deliberated (OR, 0.74; 95% CI, 0.57-0.98) were significantly more likely to make an informed choice.

CONCLUSION

The results of this study help healthcare providers, including nurses in maternity units, understand pregnant women's experiences of NIPT. Counseling strategies are needed to improve pregnant women's knowledge of NIPT and create an environment that promotes deliberation regarding this decision.

摘要

目的

本研究探讨了韩国孕妇在无创产前检测(NIPT)方面做出明智选择的程度,并调查了影响她们是否做出明智选择的因素。

方法

共有129名韩国孕妇参与了一项基于网络的调查。采用关于NIPT的明智选择和决策冲突的多维测量方法,来衡量参与者与NIPT相关的知识、态度、思考、接受程度和决策冲突水平。还询问了参与者的NIPT经历和意见的其他问题。

结果

所有129名孕妇均从一个在线社区招募。根据本研究中使用的明智选择的定义,排除那些对NIPT持中立态度的人后,只有91人做出了明智选择(n = 63,69.2%)或非明智选择(n = 28,30.8%)。在后者中,75.0%的人知识不足,39.3%的人做出了价值不一致的决定,14.3%的人没有充分思考。两组在决策冲突方面没有差异。两组在引入或推荐NIPT的原因上存在显著差异(p = 0.021)。多元逻辑回归分析表明,知识丰富(优势比[OR],4.77;95%置信区间[CI],2.17 - 10.47)且经过思考(OR,0.74;95%CI,0.57 - 0.98)的孕妇做出明智选择的可能性显著更高。

结论

本研究结果有助于包括产科护士在内的医疗保健提供者了解孕妇的NIPT经历。需要采取咨询策略来提高孕妇对NIPT的了解,并营造一个促进对此决策进行思考的环境。

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本文引用的文献

1
Nursing and advocacy in health: An integrative review.护理与健康倡导:综合述评。
Nurs Ethics. 2022 Jun;29(4):1014-1034. doi: 10.1177/09697330211062981. Epub 2022 Feb 17.
2
Experiences of non-invasive prenatal screening: A survey study.无创产前筛查的经验:一项调查研究。
Aust N Z J Obstet Gynaecol. 2022 Apr;62(2):241-249. doi: 10.1111/ajo.13436. Epub 2021 Sep 27.
3
Non-invasive prenatal test uptake in socioeconomically disadvantaged neighborhoods.社会经济条件不利社区的无创性产前检测普及率。
Prenat Diagn. 2021 Oct;41(11):1395-1400. doi: 10.1002/pd.6043. Epub 2021 Sep 14.
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Making use of non-invasive prenatal testing (NIPT): rethinking issues of routinization and pressure.利用无创性产前检测(NIPT):重新思考常规化和压力问题。
J Perinat Med. 2021 Sep 2;49(8):959-964. doi: 10.1515/jpm-2021-0236. Print 2021 Oct 26.
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Routinization of prenatal screening with the non-invasive prenatal test: pregnant women's perspectives.将非侵入性产前检测常规化用于产前筛查:孕妇的观点。
Eur J Hum Genet. 2022 Jun;30(6):661-668. doi: 10.1038/s41431-021-00940-8. Epub 2021 Aug 13.
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Decision aids for prenatal testing: A systematic review and meta-analysis.产前检测决策辅助工具:系统评价与荟萃分析
J Adv Nurs. 2021 Oct;77(10):3964-3979. doi: 10.1111/jan.14875. Epub 2021 May 3.
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Current use of noninvasive prenatal testing in Europe, Australia and the USA: A graphical presentation.当前在欧洲、澳大利亚和美国使用的非侵入性产前检测:图形展示。
Acta Obstet Gynecol Scand. 2020 Jun;99(6):722-730. doi: 10.1111/aogs.13841. Epub 2020 Apr 3.
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A two-year experience of non-invasive prenatal testing (NIPT) at an urban tertiary medical center in South Korea.韩国某城市三级医疗中心的非侵入性产前检测(NIPT)两年经验。
Taiwan J Obstet Gynecol. 2019 Jul;58(4):545-551. doi: 10.1016/j.tjog.2019.05.021.
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Perspectives of Pregnant People and Clinicians on Noninvasive Prenatal Testing: A Systematic Review and Qualitative Meta-synthesis.孕妇和临床医生对无创产前检测的看法:系统评价与定性元分析
Ont Health Technol Assess Ser. 2019 Feb 19;19(5):1-38. eCollection 2019.
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