Orofacial Pain Medicine, Department of Internal Medicine, Shaukat Khanum Memorial Cancer Hospital & Research Centers, Lahore, Pakistan.
Department of Diagnostic Sciences, Craniofacial Pain Center, Tufts University, School of Dental Medicine, Boston, MA, USA.
Dent Clin North Am. 2023 Jan;67(1):129-140. doi: 10.1016/j.cden.2022.07.010. Epub 2022 Oct 27.
Pain is a common and most debilitating symptom of head and neck cancers (HNC). The prevalence of pain in HNC is nearly 70%. There are no universally accepted classification or diagnostic criteria for HNC-related pain, and currently, HNC-related pain is classified based on the underlying pathophysiological mechanism, the location of the tumor, and the protagonist of pain. The clinical presentation of HNC-related pain varies and can be similar to primary pain disorders. The management of HNC-related pain primarily consists of pharmacotherapy. However, in some cases, interventions may be needed. This article will present a case study and review the epidemiology, diagnostic criteria and classification, clinical features, pathophysiology, and HNC-related pain management.
疼痛是头颈部癌症（HNC）的常见且最具致残性的症状。HNC 患者中疼痛的患病率接近 70%。目前，HNC 相关疼痛尚无普遍接受的分类或诊断标准，目前，HNC 相关疼痛是根据潜在的病理生理机制、肿瘤位置和疼痛主角进行分类的。HNC 相关疼痛的临床表现多种多样，可与原发性疼痛障碍相似。HNC 相关疼痛的治疗主要包括药物治疗。然而，在某些情况下，可能需要进行干预。本文将介绍一个病例研究，并回顾 HNC 相关疼痛的流行病学、诊断标准和分类、临床特征、病理生理学以及 HNC 相关疼痛的管理。
