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采用几何环瓣环成形术修复小儿及先天性心脏病患者的主动脉瓣。

Aortic valve repair using geometric ring annuloplasty in pediatric and congenital heart disease patients.

机构信息

Section of Pediatric Cardiovascular Surgery, Department of Cardiac Surgery, C.S. Mott Children's Hospital/University of Michigan, Ann Arbor, Mich.

Section of Pediatric Cardiovascular Surgery, Department of Cardiac Surgery, C.S. Mott Children's Hospital/University of Michigan, Ann Arbor, Mich.

出版信息

J Thorac Cardiovasc Surg. 2023 Aug;166(2):294-303. doi: 10.1016/j.jtcvs.2022.10.017. Epub 2022 Oct 19.

Abstract

OBJECTIVE

Existing replacement options for the aortic valve have significant drawbacks, especially in children. A geometric annuloplasty ring can help to achieve consistently successful aortic valve repair, but only limited experience with use of this device has been reported in pediatric and congenital heart disease patients.

METHODS

All pediatric and adult congenital patients at our institution who underwent aortic valve repair with placement of a geometric annuloplasty ring were reviewed. The study period spanned from July 2018 to April 2022. Hemodynamic outcomes were evaluated using transthoracic echocardiography.

RESULTS

The study included 36 subjects. The median age was 17.4 years (range, 8-30 years). Twenty-one subjects were younger than age 18 years. The most common primary diagnoses were neoaortic valve insufficiency or neoaortic root dilation, and congenital aortic stenosis with bicuspid or functionally unicuspid aortic valve. Of the 34 subjects with procedural success, 31 (91%) had use of additional valve repair techniques and 26 (76%) had an additional concomitant procedure performed. Operative mortality was 0% (0/33), and major complication rate was 6% (2/33). The median follow-up time was 1.9 years (maximum, 3.8 years). The mean grade of aortic insufficiency was signific antly reduced after repair, with no change in mean gradients. Freedom from reoperation over the follow-up period was 97% (33/34), and freedom from ≥3+ recurrent aortic insufficiency was 94% (32/34).

CONCLUSIONS

A geometric annuloplasty ring can be used to help achieve consistently successful aortic valve repair with excellent perioperative and follow-up outcomes, even in pediatric and complex congenital heart disease patients.

摘要

目的

现有的主动脉瓣置换选择方案存在明显缺陷,尤其是在儿童中。几何环成形术环有助于实现一致成功的主动脉瓣修复,但在儿科和先天性心脏病患者中,使用这种设备的经验有限。

方法

回顾了我院所有接受主动脉瓣修复并放置几何环成形术环的儿科和成人先天性心脏病患者。研究期间为 2018 年 7 月至 2022 年 4 月。使用经胸超声心动图评估血液动力学结果。

结果

研究共纳入 36 例患者。中位年龄为 17.4 岁(范围,8-30 岁)。21 例患者年龄小于 18 岁。最常见的主要诊断为新主动脉瓣关闭不全或新主动脉根部扩张,以及先天性主动脉瓣狭窄伴二叶或功能性单叶主动脉瓣。在 34 例手术成功的患者中,31 例(91%)采用了额外的瓣膜修复技术,26 例(76%)进行了额外的同期手术。手术死亡率为 0%(0/33),主要并发症发生率为 6%(2/33)。中位随访时间为 1.9 年(最长 3.8 年)。修复后主动脉瓣关闭不全的平均程度显著降低,平均梯度无变化。随访期间免于再次手术的比例为 97%(33/34),免于≥3+复发性主动脉瓣关闭不全的比例为 94%(32/34)。

结论

即使在儿科和复杂的先天性心脏病患者中,几何环成形术环也可用于帮助实现一致成功的主动脉瓣修复,具有良好的围手术期和随访结果。

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