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一种用于高分辨率 X 射线相衬断层扫描和闪烁体特性描述的多功能实验室设备。

A versatile laboratory setup for high resolution X-ray phase contrast tomography and scintillator characterization.

机构信息

Lund University, Synchrotron Radiation Research and NanoLund, Lund, Sweden.

出版信息

J Xray Sci Technol. 2023;31(1):1-12. doi: 10.3233/XST-221294.

DOI:10.3233/XST-221294
PMID:36404526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9912733/
Abstract

BACKGROUND

X-ray micro-tomography (μCT) is a powerful non-destructive 3D imaging method applied in many scientific fields. In combination with propagation-based phase-contrast, the method is suitable for samples with low absorption contrast. Phase contrast tomography has become available in the lab with the ongoing development of micro-focused tube sources, but it requires sensitive and high-resolution X-ray detectors. The development of novel scintillation detectors, particularly for microscopy, requires more flexibility than available in commercial tomography systems.

OBJECTIVE

We aim to develop a compact, flexible, and versatile μCT laboratory setup that combines absorption and phase contrast imaging as well as the option to use it for scintillator characterization. Here, we present details on the design and implementation of the setup.

METHODS

We used the setup for μCT in absorption and propagation-based phase-contrast mode, as well as to study a perovskite scintillator.

RESULTS

We show the 2D and 3D performance in absorption and phase contrast mode, as well as how the setup can be used for testing new scintillator materials in a realistic imaging environment. A spatial resolution of around 1.3μm is measured in 2D and 3D.

CONCLUSIONS

The setup meets the needs for common absorption μCT applications and offers increased contrast in phase contrast mode. The availability of a versatile laboratory μCT setup allows not only for easy access to tomographic measurements, but also enables a prompt monitoring and feedback beneficial for advances in scintillator fabrication.

摘要

背景

X 射线微断层扫描(μCT)是一种强大的非破坏性 3D 成像方法,应用于许多科学领域。与基于传播的相衬相结合,该方法适用于吸收对比度低的样品。随着微焦点管源的不断发展,相衬断层扫描已经在实验室中实现,但它需要灵敏和高分辨率的 X 射线探测器。新型闪烁体探测器的开发,特别是用于显微镜的闪烁体探测器的开发,需要比商业断层扫描系统更灵活。

目的

我们旨在开发一种紧凑、灵活和多功能的 μCT 实验室设备,该设备结合了吸收和相衬成像,以及用于闪烁体特性研究的选项。在此,我们介绍了该设备的设计和实现细节。

方法

我们使用该设备进行了吸收和基于传播的相衬模式下的 μCT 扫描,以及对钙钛矿闪烁体进行了研究。

结果

我们展示了吸收和相衬模式下的 2D 和 3D 性能,以及该设备如何在实际成像环境中用于测试新型闪烁体材料。在 2D 和 3D 中测量到约 1.3μm 的空间分辨率。

结论

该设备满足常见的吸收 μCT 应用的需求,并在相衬模式下提供了更高的对比度。多功能实验室 μCT 设备的可用性不仅允许轻松进行断层扫描测量,还能够实现对闪烁体制造进展有益的快速监测和反馈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/812c4dbbe70f/xst-31-xst221294-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/5d36588f8715/xst-31-xst221294-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/4f78c8c9771e/xst-31-xst221294-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/69be5d8b05df/xst-31-xst221294-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/77d3e8d32ae0/xst-31-xst221294-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/812c4dbbe70f/xst-31-xst221294-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/5d36588f8715/xst-31-xst221294-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/4f78c8c9771e/xst-31-xst221294-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/69be5d8b05df/xst-31-xst221294-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/77d3e8d32ae0/xst-31-xst221294-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d61/9912733/812c4dbbe70f/xst-31-xst221294-g005.jpg

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