Kryukov A I, Garov E V, Zelenkova V N, Sudarev P A, Kaloshina A S, Garova E E, Hublaryan A G, Statsenko Ya A
L.I. Sverzhevskiy Research Institute of Clinical Otorhinolaryngology, Moscow, Russia.
Pirogov Russian National Research Medical University, Moscow, Russia.
Vestn Otorinolaringol. 2022;87(5):63-69. doi: 10.17116/otorino20228705163.
Neuroendocrine adenoma (NEA) is an extremely rare pathology and accounts for less than 2% of all ear tumors. The article provides an overview of the diagnosis, classification, treatment methods and algorithm for monitoring patients with NEA of the middle ear. 6 cases of NEA of the tympanic cavity are described in detail, which were diagnosed and treated in GBUZ NIKIO named after N.N. L.I. Sverzhevsky DZM for the last 5 years. Diagnosis of NEA of the middle ear is possible when performing high-resolution multislice computed tomography of the temporal bones and magnetic resonance imaging with contrast enhancement, however, the neoplasm can be verified only after a histological examination with the determination of the immunophenotype. Differential diagnosis of NEA of the tympanic cavity with other processes of the middle ear must be carried out at each stage of the diagnostic path. Surgical treatment, depending on the volume of education, allows you to remove it completely and improve the auditory function.
神经内分泌腺瘤(NEA)是一种极为罕见的病理类型,占所有耳部肿瘤的比例不到2%。本文概述了中耳NEA患者的诊断、分类、治疗方法及监测方案。详细描述了6例鼓室NEA病例,这些病例是过去5年在以N.N. L.I. 斯韦日夫斯基命名的GBUZ NIKIO耳鼻喉科诊断和治疗的。在进行颞骨高分辨率多层计算机断层扫描和增强磁共振成像时,中耳NEA有可能被诊断出来,然而,只有在进行免疫表型测定的组织学检查后才能确诊肿瘤。在诊断过程的每个阶段都必须对鼓室NEA与中耳的其他病变进行鉴别诊断。根据病变范围进行手术治疗,能够将其完全切除并改善听觉功能。