Wang Daofeng, Han Lin, Xu Gaoxiang, Zhang Wupeng, Li Hua, Xu Cheng, Li Huanyu, Li Jitian, Zhang Hao, Li Jiantao
Department of Orthopedics, The Fourth Medical Center of Chinese PLA General Hospital, Beijing, China.
National Clinical Research Center for Orthopedics, Sports Medicine and Rehabilitation, Beijing, China.
Int J Bioprint. 2022 Aug 23;8(4):607. doi: 10.18063/ijb.v8i4.607. eCollection 2022.
Precise and shape-matching osteotomy models are determinants of the experimental homogeneity in the assessment of orthopedic biomechanical properties. At present, however, publications on detailed description of osteotomy in bone biomechanical study are scanty. The purposes of this study were to design a new method of osteotomy-aided module production for bone biomechanical study with the help of three-dimensional (3D) printing and computer-aided design (CAD) and to test the accuracy of osteotomy. Fourteen fourth-generation composite femurs were analyzed. The composite bone was scanned using computed tomography (CT) scanner and loaded in Mimics for reconstruction and, then, imported into 3-Matic software to design intertrochanteric region, distal femur, and rotation control lever models. 3D printer was used to print each component. After assembling Sawbones and osteotomy modules, a horizontal band-saw was used to create fracture models. The volume and mass of intermediate fragments were calculated and analyzed. Satisfactory osteotomies of all composite Sawbones were achieved. The mean volume and mass of intermediate fragments were 21.0 ± 1.5 mm and 19.0 ± 1.2 g, respectively. Range of deviation from average of volumes was -1.9 - 2.8 mm and most of these deviations fall within the range of -1.4 - 2.1 mm. Range of deviation from average of mass was -2.0 - 1.6 g and most of these deviations fall within the range of -1.4 - 1.6 g. One-dimensional histogram of deviation from average shows the precise and stable osteotomy performed based on the modules accordingly. A new method of osteotomy-aided module production for bone biomechanical study with the help of 3D printing and CAD was designed and the accuracy of osteotomy was verified. This method is expected to achieve homogeneity and standardization of osteotomy in bone biomechanical study.
精确且形状匹配的截骨模型是评估骨科生物力学特性时实验同质性的决定因素。然而，目前关于骨生物力学研究中截骨详细描述的出版物很少。本研究的目的是借助三维（3D）打印和计算机辅助设计（CAD）设计一种用于骨生物力学研究的新型截骨辅助模块制作方法，并测试截骨的准确性。分析了14根第四代复合股骨。使用计算机断层扫描（CT）扫描仪对复合骨进行扫描，并加载到Mimics中进行重建，然后导入到3-Matic软件中设计转子间区域、股骨远端和旋转控制杆模型。使用3D打印机打印每个组件。组装Sawbones和截骨模块后，使用水平带锯创建骨折模型。计算并分析中间碎片的体积和质量。所有复合Sawbones均实现了满意的截骨。中间碎片的平均体积和质量分别为21.0±1.5 mm和19.0±1.2 g。体积偏离平均值的范围为-1.9 - 2.8 mm，其中大部分偏差落在-1.4 - 2.1 mm范围内。质量偏离平均值的范围为-2.0 - 1.6 g，其中大部分偏差落在-1.4 - 1.6 g范围内。偏离平均值的一维直方图显示了基于模块相应进行的精确且稳定的截骨。设计了一种借助3D打印和CAD用于骨生物力学研究的新型截骨辅助模块制作方法，并验证了截骨准确性。该方法有望实现骨生物力学研究中截骨的同质性和标准化。
