Purushothaman Palani, Karpagam Subramanian
Department of Chemistry, School of Advanced Sciences, Vellore Institute of Technology, Vellore, Tamil Nadu 632014, India.
ACS Omega. 2022 Nov 2;7(45):41361-41369. doi: 10.1021/acsomega.2c05157. eCollection 2022 Nov 15.
A thirst for the development of a simple fluorescence probe for enhanced sensing application has been achieved by synthesizing a stupendous thiophene-appended benzothiazole-conjugated compound . The synthesized compound was characterized using nuclear magnetic resonance and mass spectrometry techniques. Furthermore, a photophysical property of and reveals the enhanced emission spectrum of because of a restricted spin-orbital coupling as a result of increased conjugation compared to the ligand . Therefore, comparative studies were undertaken for and . Henceforth, was deployed for the ratiometric detection of Cd ions in THF:water and for the detection of Cu ions in THF medium. The chemosensor shows an outstanding water tolerance up to 60% and is stable between pH 2 and 7. This level of water tolerance and stability make a suitable probe for analyzing real-time and biological samples. While the cadmium ion was added to , there was a significant red shift in emission from 496 to 549 nm, which indicates the controlled ICT due to complex formation. The metal-ligand complexation was also confirmed by noticing a decreased band gap of metal complex compared to the ligand as calculated using Tauc's plot with solid-phase UV data. The stoichiometric ratio was obtained by Job's plot that exhibited a 1:1 ratio of and Cd ions, and the limit of detection (LOD) was found to be 2.25 nM by the photoluminescence spectroscopic technique. The fluorescence lifetime of both and was found to be 58.3 ps and 0.147 ns, respectively. Alongside, the colorimetric-assisted ratiometric detection of Cu by with 1:2 stoichiometric ratio having an LOD of 1.06 × 10 M was also performed. Furthermore, the practical applicability of the probe in sensing cadmium was tested in sewage water and vegetable extract; the recovery was approximately 98 and 99%, respectively. The experimental data were supported by theoretical investigation of structures of , , , and , complex formation, charge transfer mechanism, and band gap measurements done by quantum chemical density functional theory calculations.
通过合成一种惊人的噻吩附加苯并噻唑共轭化合物，实现了对开发用于增强传感应用的简单荧光探针的渴望。使用核磁共振和质谱技术对合成的化合物进行了表征。此外，[此处原文可能有缺失信息]的光物理性质表明，由于与配体相比共轭增加导致自旋轨道耦合受限，[此处原文可能有缺失信息]的发射光谱增强。因此，对[此处原文可能有缺失信息]和[此处原文可能有缺失信息]进行了比较研究。此后，[此处原文可能有缺失信息]用于在四氢呋喃：水体系中对镉离子进行比率检测，[此处原文可能有缺失信息]用于在四氢呋喃介质中检测铜离子。化学传感器[此处原文可能有缺失信息]显示出高达60%的出色耐水性，并且在pH值2至7之间稳定。这种耐水性和稳定性水平使[此处原文可能有缺失信息]成为分析实时和生物样品的合适探针。当向[此处原文可能有缺失信息]中加入镉离子时，发射光谱从496 nm显著红移至549 nm，这表明由于络合物形成导致可控的电荷转移。通过使用固相紫外数据的陶氏图计算发现，与配体相比，金属络合物的带隙减小，这也证实了金属 - 配体络合。通过乔布氏图获得化学计量比，显示[此处原文可能有缺失信息]与镉离子的比例为1:1，通过光致发光光谱技术发现检测限（LOD）为2.25 nM。[此处原文可能有缺失信息]和[此处原文可能有缺失信息]的荧光寿命分别为58.3 ps和0.147 ns。此外，还进行了[此处原文可能有缺失信息]对铜的比色辅助比率检测，化学计量比为1:2，检测限为1.06×10[此处原文可能有缺失信息]M。此外，在污水和蔬菜提取物中测试了探针[此处原文可能有缺失信息]在检测镉方面的实际适用性；回收率分别约为98%和99%。通过量子化学密度泛函理论计算对[此处原文可能有缺失信息]、[此处原文可能有缺失信息]、[此处原文可能有缺失信息]和[此处原文可能有缺失信息]的结构、络合物形成、电荷转移机制和带隙测量进行理论研究，支持了实验数据。
