Pooley Rachel, Veneziano Giorgio, Burrier Candice, Tram Nguyen K, Tobias Joseph D
Heritage College of Osteopathic Medicine, Dublin Campus, Dublin, Ohio and Ohio University, Athens, OH, USA.
Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
J Clin Med Res. 2022 Oct;14(10):425-431. doi: 10.14740/jocmr4813. Epub 2022 Oct 28.
Although neuraxial techniques such as caudal and epidural anesthesia were initially the predominant regional anesthetic technique used to provide postoperative analgesia in children, there has been a transition to the use of peripheral nerve blockade such as the quadratus lumborum block (QLB). We present preliminary experience with QL catheters for continuous postoperative analgesia in a cohort of pediatric patients following colorectal surgery.
After institutional review board (IRB) approval, we retrospectively reviewed the records of patients who underwent major colorectal surgery and received QL catheters for postoperative analgesia. The postoperative pain control data consisted of QL catheter characteristics, anesthetic agents, adjuncts, pain scores, and opioid consumption during the postoperative period.
The study cohort included eight pediatric patients, ranging in age from 1 to 19 years (median age 11.8 years). The QL catheters were placed in the operating room after the induction of anesthesia. Comorbid conditions in the cohort that were contraindications to neuraxial anesthesia included spinal/vertebral malformations, presence of a ventriculoperitoneal (VP) shunt, anal atresia, tracheo-esophageal fistula (VACTERL) association, and coagulation disturbances. All patients underwent complex colorectal or genito-urologic procedures. Bilateral QL catheters were placed in six patients, and unilateral catheters were placed in two patients. Four patients received 0.5% ropivacaine and four patients received 0.2% ropivacaine of an initial bolus. The local anesthetic used for continuous infusion was 0.2% ropivacaine in five patients, 0.1% ropivacaine in two patients, and 1.5% chloroprocaine in one patient, with a median infusion rate of 0.11 mL/kg/h. QL catheter infusions were supplemented with intravenous opioids delivered by patient-controlled or nurse-controlled analgesia. The median opioid requirements in oral morphine milligram equivalents (MME) were 1.2, 1.0, 1.1, 0.5, and 0.6 MME/kg on postoperative days 1 - 5. Daily median pain scores were ≤ 2 during the 5-day postoperative course. All catheters functioned successfully and were in place for a median of 79.3 h. Other than early inadvertent removal of two catheters, no adverse effects were noted.
Although our preliminary data suggest the efficacy of QL catheters in providing prolonged postoperative analgesia for up to 3 - 5 days following colorectal procedures, attention needs to be directed at measures to ensure that the catheter is secured to avoid inadvertent removal.
尽管诸如骶管阻滞和硬膜外麻醉等神经轴技术最初是用于为儿童提供术后镇痛的主要区域麻醉技术,但现在已逐渐过渡到使用诸如腰方肌阻滞(QLB)等外周神经阻滞技术。我们介绍了在一组接受结直肠手术的儿科患者中使用QL导管进行持续术后镇痛的初步经验。
经机构审查委员会(IRB)批准后,我们回顾性地审查了接受大型结直肠手术并接受QL导管进行术后镇痛的患者记录。术后疼痛控制数据包括QL导管特征、麻醉剂、辅助药物、疼痛评分以及术后期间的阿片类药物消耗量。
研究队列包括8名儿科患者,年龄从1岁到19岁不等(中位年龄11.8岁)。QL导管在麻醉诱导后于手术室放置。该队列中作为神经轴麻醉禁忌证的合并症包括脊柱/椎体畸形、存在脑室腹腔(VP)分流管、肛门闭锁、气管食管瘘(VACTERL)综合征以及凝血功能障碍。所有患者均接受了复杂的结直肠或泌尿生殖系统手术。6例患者放置了双侧QL导管,2例患者放置了单侧导管。4例患者初始推注接受了0.5%的罗哌卡因,4例患者接受了0.2%的罗哌卡因。5例患者持续输注使用的局部麻醉药为0.2%的罗哌卡因,2例患者为0.1%的罗哌卡因,1例患者为1.5%的氯普鲁卡因,中位输注速率为0.11 mL/kg/h。QL导管输注辅以通过患者自控或护士控制镇痛给予的静脉阿片类药物。术后第1至5天口服吗啡毫克当量(MME)的中位阿片类药物需求量分别为1.2、1.0、1.1、0.5和0.6 MME/kg。术后5天每日中位疼痛评分≤2分。所有导管均成功发挥作用,中位留置时间为79.3小时。除了早期有2根导管意外拔除外,未观察到其他不良反应。
尽管我们的初步数据表明QL导管在结直肠手术后长达3至5天提供延长的术后镇痛方面有效,但需要注意采取措施确保导管固定,以避免意外拔除。