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超声引导下腰方肌阻滞与尾端注射罗哌卡因/吗啡用于小儿膀胱输尿管反流手术的比较

Ultrasound-guided quadratus lumborum block compared to caudal ropivacaine/morphine in children undergoing surgery for vesicoureteric reflex.

作者信息

Sato Makoto

机构信息

Department of Anesthesiology, Tokyo Metropolitan Children's Medical Center, Fuchu, Tokyo, Japan.

出版信息

Paediatr Anaesth. 2019 Jul;29(7):738-743. doi: 10.1111/pan.13650. Epub 2019 Jun 2.

Abstract

BACKGROUND

Ultrasound-guided quadratus lumborum block is a regional anesthetic technique which can provide perioperative analgesia for all age groups, including pediatric patients undergoing abdominal surgery. We hypothesized that the quadratus lumborum block would be as efficacious as a caudal block, the gold standard of pediatric lower abdominal regional anesthesia, in providing pain control after ureteral reimplantation but also have a longer duration.

METHODS

Forty-seven pediatric patients between the ages of 1 and 17 years undergoing bilateral ureteral reimplantation surgery via a low transverse incision were enrolled and randomized into the quadratus lumborum block and caudal block groups. All blocks were performed preoperatively under general anesthesia. We analyzed the following outcomes: the requirement for narcotic analgesics, pain score, episodes of emesis, and complications at 0, 4, 24, and 48 hours postoperatively.

RESULTS

The study included 44 patients after excluding three who were ineligible. The fentanyl requirement for postoperative rescue analgesia during the first 24 hours was significantly lower in the quadratus lumborum block group than in the caudal block group (median [interquartile range]: 0 [0-1] vs 3 [0-5], P = 0.016, 95% confidence intervals: -4 to 0) but not at 30 minutes, 4, or 48 hours. No significant difference was observed in the pain scores or the incidence of interventions to treat nausea and vomiting during the entire period. No postoperative complication was observed.

CONCLUSION

The quadratus lumborum block was more effective in reducing the postoperative opioid requirement for rescue analgesia during the initial 24 hours than caudal ropivacaine/morphine.

摘要

背景

超声引导下腰方肌阻滞是一种区域麻醉技术,可为所有年龄组提供围手术期镇痛,包括接受腹部手术的儿科患者。我们假设,腰方肌阻滞在输尿管再植术后控制疼痛方面与小儿下腹部区域麻醉的金标准——骶管阻滞一样有效,但作用持续时间更长。

方法

纳入47例年龄在1至17岁之间、经低位横切口行双侧输尿管再植手术的儿科患者,并随机分为腰方肌阻滞组和骶管阻滞组。所有阻滞均在全身麻醉下于术前进行。我们分析了以下结果:术后0、4、24和48小时的麻醉性镇痛药需求、疼痛评分、呕吐发作情况及并发症。

结果

排除3例不符合条件的患者后,研究共纳入44例患者。腰方肌阻滞组术后前24小时用于补救镇痛的芬太尼需求量显著低于骶管阻滞组(中位数[四分位间距]:0[0 - 1] 比 3[0 - 5],P = 0.016,95%置信区间:-4至0),但在30分钟、4小时或48小时时无显著差异。在整个期间,疼痛评分或治疗恶心和呕吐的干预发生率均无显著差异。未观察到术后并发症。

结论

在术后最初24小时内,腰方肌阻滞在减少补救镇痛的术后阿片类药物需求方面比骶管注射罗哌卡因/吗啡更有效。

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