恙虫病所致急性呼吸窘迫综合征经甲泼尼龙冲击及治疗性血浆置换后快速康复
Rapid Recovery of Acute Respiratory Distress Syndrome in Scrub Typhus, With Pulse Methylprednisolone and Therapeutic Plasma Exchange.
作者信息
Rathnasekara Thilina, Wijekoon Lanka, Senanayake Hemal, Siribaddana Sisira
机构信息
Internal Medicine, Postgraduate Institute of Medicine, University of Colombo, Colombo, LKA.
Medicine, Faculty of Medicine, University of Rajarata, Anuradhapura, LKA.
出版信息
Cureus. 2022 Oct 15;14(10):e30329. doi: 10.7759/cureus.30329. eCollection 2022 Oct.
Acute respiratory distress syndrome (ARDS) is an atypical presentation of scrub typhus infection with associated high morbidity and mortality compared to uncomplicated scrub typhus infection. Here we report an otherwise healthy 41-year-old female patient admitted with moderate ARDS secondary to scrub typhus infection who gained comparatively rapid recovery within 72 hours following intravenous methylprednisolone pulse (MPP) therapy with therapeutic plasma exchange (TPE), suggesting a beneficial role of MPP and TPE in the treatment of ARDS secondary to scrub typhus infection. To our knowledge, this is the first case report regarding the use of MPP therapy and TPE in a patient with ARDS due to scrub typhus infection.
急性呼吸窘迫综合征（ARDS）是恙虫病感染的一种非典型表现，与无并发症的恙虫病感染相比，其发病率和死亡率较高。在此，我们报告一名41岁的健康女性患者，因恙虫病感染继发中度ARDS入院，在接受静脉注射甲泼尼龙冲击（MPP）治疗并联合治疗性血浆置换（TPE）后，于72小时内较快康复，提示MPP和TPE在治疗恙虫病感染继发的ARDS中具有有益作用。据我们所知，这是首例关于在恙虫病感染所致ARDS患者中使用MPP治疗和TPE的病例报告。
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