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肯尼亚高血压男性的勃起功能障碍:一家三级转诊医院的经验。

Erectile dysfunction in hypertensive males in Kenya: a tertiary referral hospital experience.

机构信息

University of Nairobi, College of Health Sciences, East African Kidney Institute, Nairobi, Kenya.

University of Nairobi, College of Health Sciences, Department of Clinical Medicine and Therapeutics, Nairobi Kenya.

出版信息

Afr Health Sci. 2022 Jun;22(2):420-427. doi: 10.4314/ahs.v22i2.48.

Abstract

UNLABELLED

Erectile dysfunction (ED) in males can be organic or/and psychological.

OBJECTIVE

To determine the burden of ED among adult hypertensive men attending ambulatory clinic at Kenyatta National Hospital, Nairobi, Kenya.

METHODS

Descriptive cross-sectional study on patients on antihypertensive medications, followed for ≥ one month. The tools used were five-item International Index of Erectile Function (IIEF-5) for ED and Alcohol Use Disorders Identification Test for alcohol use.

RESULTS

Among 385 patients, the mean age was 56.2 ±11.3 years, median follow up in medical clinic was 5 years. The mean body mass index was 26.3 ± 4.6 kg/m2, 209(54.3%) were pre-obese/obese. Current smokers were 76(19.7%) while 133(34.5%) were former smokers. Alcohol use in the past year was reported by 256(68.5%), while hazardous alcohol intake was in 54(14%). Prescribed antihypertensives in various combinations included angiotensin converting enzyme inhibitors/angiotensin receptor blockers to 292(75.8%), calcium channel blockers to 238(61.8%), beta blockerso 129(33.5%) and thiazide diuretics on 77(20%). Using IIEF-5 tool, the prevalence of ED was 364(94.5%) (95%CI 92.2-96.6) distributed as mild in 255(70%), moderate 76(21.9%) and 33(9.1%) severe.

CONCLUSION

The burden of ED is high among hypertensive males. Precipitants of ED like cigarette smoking and alcohol use and use of antihypertensives which can cause ED are prevalent too.

摘要

目的

确定在肯尼亚内罗毕肯雅塔国家医院接受门诊治疗的成年高血压男性中勃起功能障碍(ED)的负担。

方法

这是一项针对接受降压药物治疗、随访时间≥1 个月的患者的描述性横断面研究。使用的工具包括用于 ED 的 5 项国际勃起功能指数(IIEF-5)和用于酒精使用的酒精使用障碍识别测试。

结果

在 385 名患者中,平均年龄为 56.2±11.3 岁,在医疗诊所的中位随访时间为 5 年。平均体重指数为 26.3±4.6kg/m2,209 名(54.3%)为超重/肥胖。目前吸烟者为 76 名(19.7%),而 133 名(34.5%)为曾经吸烟者。过去一年报告饮酒的有 256 名(68.5%),而危险饮酒的有 54 名(14%)。各种组合的降压药物包括血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂 292 名(75.8%)、钙通道阻滞剂 238 名(61.8%)、β受体阻滞剂 129 名(33.5%)和噻嗪类利尿剂 77 名(20%)。使用 IIEF-5 工具,ED 的患病率为 364 名(94.5%)(95%CI 92.2-96.6),分布为轻度 255 名(70%)、中度 76 名(21.9%)和 33 名(9.1%)严重。

结论

高血压男性中 ED 的负担很高。ED 的诱发因素,如吸烟和饮酒以及可能导致 ED 的降压药物的使用也很普遍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b7e/9652675/d2116c6549f9/AFHS2202-0420Fig1.jpg

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