Equipo de Atención Primaria, Vilagarcía de Arousa, Pontevedra, España.
Unidad de Epidemiología Clínica e Investigación Bioestadística, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, Universidade da Coruña, A Coruña, España.
Med Clin (Barc). 2019 Mar 15;152(6):209-215. doi: 10.1016/j.medcli.2018.05.022. Epub 2018 Jul 8.
Estimate the frequency of erectile dysfunction in patients with essential hypertension and associated variables, degree of control, cardiovascular risk and the impact on quality of life.
Type of study: Observational study of prevalence in men with essential hypertension.
Sociodemographic and comorbidity variables were collected from each patient (age, Charlson index, dyslipidaemia and prostatic hyperplasia), degree of control of essential hypertension and treatment, cardiovascular risk and metabolic syndrome. The erectile dysfunction was diagnosed by the International Index of Erectile Function (IIEF-15). Quality of life questionnaires were carried out in essential hypertension (MINICHAL), and the international scale of prostatic symptoms (IPSS).
The study included 262 hypertensive men with an average age of 65.84years. Erectile dysfunction was presented in 46.1%, being severe in 54.9%. The bivariate analysis shows an independent association between erectile dysfunction and the variables: age, Charlon index, dyslipidaemia, benign prostatic hypertrophy, diastolic blood pressure, years of diagnosis of hypertension, number of treatments, Regicor and Framingham-Wilson, glycaemia, creatinine and GPT, glomerular filtration through the MDRD formula, irritative symptomatology (IPSS) and somatic manifestations (MINICHAL). The final multivariate model found association with age, presentation of dyslipidaemia, prostatic hyperplasia and metabolic syndrome.
Erectile dysfunction is significantly associated with age, dyslipidaemia, benign prostatic hypertrophy and metabolic syndrome.
估计原发性高血压患者勃起功能障碍的频率及相关变量、控制程度、心血管风险以及对生活质量的影响。
这是一项原发性高血压男性患者患病率的观察性研究。
从每位患者收集社会人口统计学和合并症变量（年龄、Charlson 指数、血脂异常和前列腺增生）、原发性高血压的控制程度和治疗、心血管风险和代谢综合征。勃起功能障碍通过国际勃起功能指数（IIEF-15）进行诊断。对原发性高血压患者进行生活质量问卷（MINICHAL）和国际前列腺症状评分（IPSS）调查。
研究纳入了 262 名平均年龄为 65.84 岁的原发性高血压男性患者。46.1%的患者存在勃起功能障碍，其中 54.9%为重度。单变量分析显示，勃起功能障碍与年龄、Charlon 指数、血脂异常、良性前列腺增生、舒张压、高血压诊断年限、治疗次数、Regicor 和 Framingham-Wilson、血糖、肌酐和 GPT、MDRD 公式估算的肾小球滤过率、刺激症状（IPSS）和躯体症状（MINICHAL）等变量存在独立相关性。最终的多变量模型发现与年龄、血脂异常、前列腺增生和代谢综合征有关。
勃起功能障碍与年龄、血脂异常、良性前列腺增生和代谢综合征显著相关。
