Faculty of Medical Sciences, Lebanese University, Hadath, Lebanon.
Neuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Hadath, Lebanon.
Afr Health Sci. 2022 Jun;22(2):116-124. doi: 10.4314/ahs.v22i2.14.
Acute flaccid paralysis (AFP) is a clinical syndrome characterized by the acute onset of weakness and paralysis with reduced muscle tone. This study explored the incidence and different aspects of AFP in Lebanese children between 2009 and 2019.
AFP data were collected from the Lebanese Ministry of Public Health. Incidence rate according to year, age groups, clinical data, follow-up, diagnosis, and vaccination status was analyzed in the 11-years period.
AFP incidence rates increased importantly from 0.63 per 100,000 in 2009 till 4.96 per 100,000 in 2019. Most of the patients were children under ten years of age, 40.6% of all cases were under five years old, and 37.9% were between 5 and 9 years old. Follow-up revealed that approximately two out of five patients experienced residual weakness. As for the final diagnosis, around 30% of cases were diagnosed as Guillain-Barre Syndrome (GBS). Most cases were children having received between 3 and 5 doses of polio vaccine.
The rise in cases coincided with the Syrian refugee crisis in Lebanon and the progressively deteriorating economy in the country; yet, incidence rates were in the lower margin compared with other countries.
急性弛缓性麻痹（AFP）是一种以急性起病、肌无力和弛缓性瘫痪为特征的临床综合征，伴有肌张力降低。本研究旨在探讨 2009 年至 2019 年期间黎巴嫩儿童 AFP 的发病率和不同方面。
从黎巴嫩公共卫生部收集 AFP 数据。在 11 年期间，根据年份、年龄组、临床数据、随访、诊断和疫苗接种状况分析发病率。
AFP 发病率从 2009 年的 0.63/10 万显著增加到 2019 年的 4.96/10 万。大多数患者为 10 岁以下儿童，40.6%的病例年龄在 5 岁以下，37.9%的病例年龄在 5-9 岁之间。随访显示，约五分之二的患者存在残留肌无力。最终诊断方面，约 30%的病例诊断为格林-巴利综合征（GBS）。大多数病例为接受了 3 至 5 剂脊髓灰质炎疫苗的儿童。
病例的增加与黎巴嫩的叙利亚难民危机以及该国经济的逐渐恶化相吻合；然而，与其他国家相比，发病率仍处于较低水平。
