Mansoura Nephrology and Dialysis unit, Mansoura University, Faculty of Medicine, El Gomhurria st, Mansoura, Egypt, Zip code: 35516.
Afr Health Sci. 2022 Jun;22(2):350-361. doi: 10.4314/ahs.v22i2.40.
Acute Kidney Injury (AKI) is a public health problem. Elderly present a greater predisposition to the development of AKI, either due to kidney senility, or due to high prevalence of comorbidities and polypharmacy. Considering the scarcity of studies on AKI in the elderly particularly in developing countries, this study emphasizes on the pattern and outcome of AKI in the Egyptian elderly.
To analyze the demographics, risk factors and outcomes of Acute Kidney Injury (AKI) in the Egyptian elderly.
A total of 199 patients were included over one year and were divided into two groups; group I (79 elderly patients) and group II (120 non-elderly patients). The two groups were compared regarding demographics, risk factors and major outcomes including patient and renal survival.
Elderly patients showed a higher prevalence of Diabetes Mellitus and chronic kidney disease (p=0.004 and 0.005 respectively). Pre-renal causes of AKI principally dehydration represented the major risk factor (p=0.003). Sepsis and hypertension predicted mortality in the elderly (p=0.001 and 0.035 respectively).
In our locality; the elderly is highly vulnerable to AKI. Pre-renal causes principally dehydration represent the main triggers of AKI. Sepsis and hypertension contribute to mortality in this population. Preventive strategies are crucial not only in the hospital but also at home.
急性肾损伤（AKI）是一个公共卫生问题。老年人更容易发生 AKI，这可能是由于肾脏老化，也可能是由于合并症和多种药物治疗的高发。考虑到在发展中国家，特别是在老年人中，AKI 的研究稀缺，本研究强调了埃及老年人中 AKI 的模式和结局。
分析埃及老年人急性肾损伤（AKI）的人口统计学、危险因素和结局。
在一年的时间里，共纳入了 199 名患者，并将他们分为两组；第 I 组（79 名老年患者）和第 II 组（120 名非老年患者）。比较两组的人口统计学、危险因素和主要结局，包括患者和肾脏存活率。
老年患者中糖尿病和慢性肾脏病的患病率更高（p=0.004 和 0.005）。AKI 的肾前性病因主要是脱水，这是主要的危险因素（p=0.003）。败血症和高血压预测老年人的死亡率（p=0.001 和 0.035）。
在我们的地区，老年人极易发生 AKI。肾前性病因主要是脱水，是 AKI 的主要触发因素。败血症和高血压导致该人群的死亡率增加。预防策略不仅在医院，而且在家庭中都至关重要。
