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老年人群中的原发性甲状旁腺功能亢进症：一例病例报告及文献综述

Primary hyperparathyroidism in the geriatric population: A case report and mini literature review.

作者信息

Jaisinghani Priya, Sharma Anupa, Wang Xiangbang

机构信息

Division of Endocrinology, Metabolism, and Nutrition, Department of Medicine New York University School of Medicine New Brunswick New Jersey USA.

Division of Endocrinology, Metabolism, and Nutrition, Department of Medicine Rutgers University-Robert Wood Johnson Medical School New Brunswick New Jersey USA.

出版信息

Clin Case Rep. 2022 Nov 16;10(11):e6313. doi: 10.1002/ccr3.6313. eCollection 2022 Nov.

DOI:10.1002/ccr3.6313
PMID:36408083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9669393/
Abstract

We report a case of a 93-year-old woman with PHPT secondary to a left inferior parathyroid adenoma. The patient met criteria to be a surgical candidate; however, literature about parathyroidectomy in the elderly was limited and controversial. The patient remained stable through medical management for the next 5 years.

摘要

我们报告了一例93岁女性因左下方甲状旁腺腺瘤继发甲状旁腺功能亢进症（PHPT）的病例。该患者符合手术候选标准；然而，关于老年人甲状旁腺切除术的文献有限且存在争议。在接下来的5年里，该患者通过药物治疗保持稳定。

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本文引用的文献

1
Therapeutic Challenges for Elderly Patients with Primary Hyperparathyroidism.老年原发性甲状旁腺功能亢进患者的治疗挑战
Case Rep Endocrinol. 2019 Oct 23;2019:4807081. doi: 10.1155/2019/4807081. eCollection 2019.
2
Primary Hyperparathyroidism.原发性甲状旁腺功能亢进症。
J Clin Endocrinol Metab. 2018 Nov 1;103(11):3993-4004. doi: 10.1210/jc.2018-01225.
3
Contemporary Medical Management of Primary Hyperparathyroidism: A Systematic Review.原发性甲状旁腺功能亢进症的当代医学管理：一项系统评价。
Front Endocrinol (Lausanne). 2017 Apr 20;8:79. doi: 10.3389/fendo.2017.00079. eCollection 2017.
4
Treatment of Nonagenarians with Primary Hyperparathyroidism.
J Am Geriatr Soc. 2016 Oct;64(10):e112-e113. doi: 10.1111/jgs.14412. Epub 2016 Aug 26.
5
Is surgery necessary for 'mild' or 'asymptomatic' hyperparathyroidism?“轻度”或“无症状”甲状旁腺功能亢进症是否需要手术治疗？
Eur J Endocrinol. 2015 Sep;173(3):D13-20. doi: 10.1530/EJE-15-0277. Epub 2015 Jun 22.
6
Parathyroidectomy Halts the Deterioration of Renal Function in Primary Hyperparathyroidism.甲状旁腺切除术可阻止原发性甲状旁腺功能亢进症患者肾功能的恶化。
J Clin Endocrinol Metab. 2015 Aug;100(8):3069-73. doi: 10.1210/jc.2015-2132. Epub 2015 Jun 16.
7
Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop.无症状原发性甲状旁腺功能亢进症管理指南：第四届国际研讨会总结声明
J Clin Endocrinol Metab. 2014 Oct;99(10):3561-9. doi: 10.1210/jc.2014-1413. Epub 2014 Aug 27.
8
Comparison of outcome between older and younger patients following surgery for primary hyperparathyroidism.原发性甲状旁腺功能亢进症手术后老年患者与年轻患者的预后比较。
Pol Przegl Chir. 2013 Oct;85(10):598-604. doi: 10.2478/pjs-2013-0089.
9
Comparison of alendronate and raloxifene for the management of primary hyperparathyroidism.阿仑膦酸钠与雷洛昔芬治疗原发性甲状旁腺功能亢进症的比较。
J Endocrinol Invest. 2013 Dec;36(11):1076-82. doi: 10.3275/9095. Epub 2013 Sep 27.
10
Skeletal effects of primary hyperparathyroidism: bone mineral density and fracture risk.原发性甲状旁腺功能亢进的骨骼影响：骨密度和骨折风险。
J Clin Densitom. 2013 Jan-Mar;16(1):28-32. doi: 10.1016/j.jocd.2012.11.013.