获得性葡萄酒色斑：两例报告及文献综述。
Acquired port-wine stains: A report of two cases and review of the literature.
作者信息
Saliba Elie, Yumeen Sara, Tannous Zeina
机构信息
Department of Dermatology, Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon.
Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
出版信息
J Cosmet Dermatol. 2023 Mar;22(3):945-948. doi: 10.1111/jocd.15526. Epub 2022 Nov 21.
BACKGROUND
Acquired port-wine stains (APWS) are rare vascular malformations that share the same clinical and histological features as their congenital counterparts. Rare cases of AWPS secondary to trauma or in association with medications have been reported in the literature.
PATIENTS AND METHODS
We report two cases of APWS. One case appeared at the age of 2 months, the earliest reported in the literature and continued to evolve till the age of 3 years presenting with multifocal distribution mainly affecting the lower face. The second case developed during oral isotretinoin intake and persisted after discontinuation of the treatment.
RESULTS AND CONCLUSIONS
The second patient declined treatment, but the first patient had a remarkable improvement following treatment with the pulsed dye laser, which remains the standard of care for capillary malformations on the face.
背景
获得性葡萄酒色斑（APWS）是罕见的血管畸形，与先天性葡萄酒色斑具有相同的临床和组织学特征。文献中报道过继发于创伤或与药物相关的罕见APWS病例。
患者与方法
我们报告两例APWS。一例在2个月大时出现，是文献中报道的最早病例，持续发展至3岁，表现为多灶性分布，主要累及下面部。第二例在口服异维A酸期间出现，并在停药后持续存在。
结果与结论
第二例患者拒绝治疗，但第一例患者在接受脉冲染料激光治疗后有显著改善，脉冲染料激光仍是面部毛细血管畸形的标准治疗方法。
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