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慢性精神疾病患者长期护理机构中 COVID-19 的发病率、住院率、死亡率及风险因素

Incidence, Hospitalization, Mortality and Risk Factors of COVID-19 in Long-Term Care Residential Homes for Patients with Chronic Mental Illness.

作者信息

Arnedo-Pena Alberto, Romeu-Garcia María Angeles, Gasco-Laborda Juan Carlos, Meseguer-Ferrer Noemi, Safont-Adsuara Lourdes, Guillen-Grima Francisco, Tirado-Balaguer María Dolores, Sabater-Vidal Susana, Gil-Fortuño María, Pérez-Olaso Oscar, Hernández-Pérez Noelia, Moreno-Muñoz Rosario, Bellido-Blasco Juan

机构信息

Epidemiology Division, Public Health Center, 12003 Castelló de la Plana, Spain.

Public Health and Epidemiology (CIBERESP), 28029 Madrid, Spain.

出版信息

Epidemiologia (Basel). 2022 Sep 8;3(3):391-401. doi: 10.3390/epidemiologia3030030.

Abstract

Long-term care residential homes (LTCRH) for patients with chronic mental illness have suffered the enormous impact of COVID-19. This study aimed to estimate incidence, hospitalization, mortality, and risk factors of COVID-19 to prevent future epidemics. From March 2020 to January 2021 and before vaccination anti-SARS-CoV-2 begins, cumulate incidence rate (CIR), hospitalization rate (HR), mortality rate (MR), and risk factors of COVID-19 in the 11 LTCRH of two Health Departments of Castellon (Spain) were studied by epidemiological surveillance and an ecological design. Laboratory tests confirmed COVID-19 cases, and multilevel Poisson regression models were employed. All LTCRH participated and comprised 346 residents and 482 staff. Residents had a mean age of 47 years, 40% women, and suffered 75 cases of COVID-19 (CIR = 21.7%), five hospitalizations (HR = 1.4%), and two deaths (MR = 0.6%) with 2.5% fatality-case. Staff suffered 74 cases of the disease (CIR = 15.4%), one hospitalization (HR = 0.2%), and no deaths were reported. Risk factors associated with COVID-19 incidence in residents were private ownership, severe disability, residents be younger, CIR in municipalities where LTCRH was located, CIR in staff, and older age of the facilities. Conclusion: COVID-19 incidence could be prevented by improving infection control in residents and staff and modernizing facilities with increased public ownership.

摘要

为慢性精神疾病患者提供服务的长期护理养老院受到了新冠疫情的巨大冲击。本研究旨在评估新冠病毒病的发病率、住院率、死亡率及风险因素,以预防未来的疫情。在2020年3月至2021年1月期间,且在开始接种抗SARS-CoV-2疫苗之前,通过流行病学监测和生态设计,对西班牙卡斯特利翁两个卫生部门的11家长期护理养老院中新冠病毒病的累积发病率(CIR)、住院率(HR)、死亡率(MR)及风险因素进行了研究。通过实验室检测确诊新冠病毒病病例,并采用多水平泊松回归模型。所有长期护理养老院均参与研究,共纳入346名居民和482名工作人员。居民的平均年龄为47岁,女性占40%,发生了75例新冠病毒病(CIR = 21.7%),5例住院(HR = 1.4%),2例死亡(MR = 0.6%),病死率为2.5%。工作人员发生了74例该病(CIR = 15.4%),1例住院(HR = 0.2%),未报告死亡病例。与居民新冠病毒病发病率相关的风险因素包括私立性质、重度残疾、居民年龄较轻、长期护理养老院所在市镇的CIR、工作人员的CIR以及机构的年限较长。结论:通过改善居民和工作人员的感染控制措施以及提高公有化程度对设施进行现代化改造,可以预防新冠病毒病的发生。

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