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Managing Malignant Pleural Mesothelioma in the Age of Personalized Medicine: Where Are We and What Is Still Missing?个性化医疗时代的恶性胸膜间皮瘤管理：我们目前的状况及仍存在的不足？
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New Updates of the Imaging Role in Diagnosis, Staging, and Response Treatment of Malignant Pleural Mesothelioma.影像检查在恶性胸膜间皮瘤诊断、分期及治疗反应评估中的新进展
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Activation of DNA Damage Tolerance Pathways May Improve Immunotherapy of Mesothelioma.激活DNA损伤耐受途径可能改善间皮瘤的免疫治疗。
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NF2 and Canonical Hippo-YAP Pathway Define Distinct Tumor Subsets Characterized by Different Immune Deficiency and Treatment Implications in Human Pleural Mesothelioma.NF2与经典的Hippo-YAP信号通路界定了人类胸膜间皮瘤中不同的肿瘤亚群，这些亚群具有不同的免疫缺陷特征及治疗意义。
Cancers (Basel). 2021 Mar 29;13(7):1561. doi: 10.3390/cancers13071561.
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C1q-HA Matrix Regulates the Local Synthesis of Hyaluronan in Malignant Pleural Mesothelioma by Modulating HAS3 Expression.C1q-透明质酸基质通过调节HAS3表达来调控恶性胸膜间皮瘤中透明质酸的局部合成。
Cancers (Basel). 2021 Jan 22;13(3):416. doi: 10.3390/cancers13030416.
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Establishment and Characterization of Patient-Derived Xenografts (PDXs) of Different Histology from Malignant Pleural Mesothelioma Patients.恶性胸膜间皮瘤患者不同组织学类型的患者来源异种移植瘤（PDXs）的建立与表征
Cancers (Basel). 2020 Dec 20;12(12):3846. doi: 10.3390/cancers12123846.

个性化医疗时代的恶性胸膜间皮瘤管理：我们目前的状况及仍存在的不足？

Managing Malignant Pleural Mesothelioma in the Age of Personalized Medicine: Where Are We and What Is Still Missing?

作者信息

Stella Giulia Maria, Bortolotto Chandra

机构信息

Department of Internal Medicine and Medical Therapeutics, University of Pavia Medical School, 27100 Pavia, Italy.

Cardio-Thoraco-Vascular Department, Unit of Respiratory Diseases, IRCCS Policlinico San Matteo Foundation and University of Pavia Medical School, 27100 Pavia, Italy.

出版信息

Cancers (Basel). 2022 Nov 11;14(22):5540. doi: 10.3390/cancers14225540.

DOI:10.3390/cancers14225540
PMID:36428633
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9688431/
Abstract

Malignant Mesothelioma (MM) is an aggressive neoplasm of the pleural mesothelium, less frequently peritoneal and exceptionally of the vaginal tunic of the testicle and pericardium [...].

摘要

恶性间皮瘤（MM）是一种侵袭性的胸膜间皮肿瘤，较少发生于腹膜，罕见于睾丸鞘膜和心包膜[……]