Romei Chiara, Fanni Salvatore Claudio, Volpi Federica, Milazzo Alessio, D'Amore Caterina Aida, Colligiani Leonardo, Neri Emanuele, De Liperi Annalisa, Stella Giulia Maria, Bortolotto Chandra
2nd Radiology Unit, Radiology Department, Pisa University Hospital, 56124 Pisa, Italy.
Department of Translational Research, Academic Radiology, University of Pisa, 56124 Pisa, Italy.
Cancers (Basel). 2021 Aug 30;13(17):4377. doi: 10.3390/cancers13174377.
Malignant pleural mesothelioma is a rare neoplasm with poor prognosis. CT is the first imaging technique used for diagnosis, staging, and assessment of therapy response. Although, CT has intrinsic limitations due to low soft tissue contrast and the current staging system as well as criteria for evaluating response, it does not consider the complex growth pattern of this tumor. Computer-based methods have proven their potentiality in diagnosis, staging, prognosis, and assessment of therapy response; moreover, computer-based methods can make feasible tasks like segmentation that would otherwise be impracticable. MRI, thanks to its high soft tissue contrast evaluation of contrast enhancement and through diffusion-weighted-images, could replace CT in many clinical settings.
恶性胸膜间皮瘤是一种预后较差的罕见肿瘤。CT是用于诊断、分期及评估治疗反应的首选成像技术。尽管CT由于软组织对比度低以及当前的分期系统和评估反应的标准而存在固有局限性，但它并未考虑该肿瘤复杂的生长模式。基于计算机的方法已在诊断、分期、预后及治疗反应评估中证明了其潜力；此外，基于计算机的方法可完成如分割等原本不可行的任务。MRI凭借其对对比增强的高软组织对比度评估以及通过扩散加权成像，在许多临床情况下可替代CT。
