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核心技术专利：CN118964589B侵权必究
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Simultaneous Determination of 11 Mycotoxins in Maize via Multiple-Impurity Adsorption Combined with Liquid Chromatography-Tandem Mass Spectrometry.

作者信息

Guan Xin, Feng Yuchao, Suo Decheng, Xiao Zhiming, Wang Shi, Liang Ying, Fan Xia

机构信息

College of Food, Heilongjiang Bayi Agricultural University, Daqing 163000, China.

Institute of Agricultural Quality Standards and Testing Technology, Chinese Academy of Agricultural Sciences, Beijing 100081, China.

出版信息

Foods. 2022 Nov 13;11(22):3624. doi: 10.3390/foods11223624.

DOI:10.3390/foods11223624
PMID:36429216
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9689081/
Abstract

In this study, multiple-impurity adsorption purification (MIA) technologies and liquid chromatography−tandem mass spectrometry (LC-MS/MS) were used to establish a method for detecting 11 mycotoxins in maize. The conditions for mass spectrometry and MIA were optimized. Maize was extracted with 70% acetonitrile solution, enriched, and purified using MIA technologies, and then, analyzed via LC-MS/MS. The results showed that the linear correlation coefficients of the 11 mycotoxins were >0.99, the sample recoveries ranged from 77.5% to 98.4%, and the relative standard deviations were <15%. The validated method was applied to investigate actual samples, and the results showed that the main contaminating toxins in maize were aflatoxins (AFs), deoxynivalenol (DON), fumonisins (FBs), ochratoxin A (OTA), and zearalenone (ZEN). Additionally, simultaneous contamination by multiple toxins was common. The maximum detection values of the mycotoxins were 77.65, 1280.18, 200,212.41, 9.67, and 526.37 μg/kg for AFs, DON, FBs, OTA, and ZEN, respectively. The method is simple in pre-treatment, convenient in operation, and suitable for the simultaneous determination of 11 types of mycotoxins in maize.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/056d55a6bf50/foods-11-03624-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/1fafafe78340/foods-11-03624-g0A1a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/781279cf1e88/foods-11-03624-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/b1747303e031/foods-11-03624-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/763a97498f80/foods-11-03624-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/6ab5a86ffa04/foods-11-03624-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/29b87f849840/foods-11-03624-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/c75536093817/foods-11-03624-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/056d55a6bf50/foods-11-03624-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/1fafafe78340/foods-11-03624-g0A1a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/781279cf1e88/foods-11-03624-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/b1747303e031/foods-11-03624-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/763a97498f80/foods-11-03624-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/6ab5a86ffa04/foods-11-03624-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/29b87f849840/foods-11-03624-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/c75536093817/foods-11-03624-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27ee/9689081/056d55a6bf50/foods-11-03624-g007.jpg

相似文献

[1]
Simultaneous Determination of 11 Mycotoxins in Maize via Multiple-Impurity Adsorption Combined with Liquid Chromatography-Tandem Mass Spectrometry.

Foods. 2022-11-13

[2]
Development and application of a method for the analysis of 9 mycotoxins in maize by HPLC-MS/MS.

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[3]
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[4]
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[5]
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[6]
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[7]
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[8]
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Anal Bioanal Chem. 2011-9-4

[9]
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[10]
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引用本文的文献

[1]
Ion source component development for ambient mass spectrometry-based mycotoxin detection in ready-to-eat corn.

Mikrochim Acta. 2025-7-4

[2]
Research Progress and Management Strategies for the Common Mycotoxin Contamination of Traditional Chinese Medicines.

J Fungi (Basel). 2025-5-27

[3]
Rapid screening of fumonisins in maize using near-infrared spectroscopy (NIRS) and machine learning algorithms.

Food Chem X. 2025-3-10

[4]
Development of a Sensitive Enzyme Immunoassay Using Phage-Displayed Antigen-Binding Fragments for Zearalenone Detection in Cereal Samples.

Foods. 2025-2-22

[5]
Simultaneous Determination of Aflatoxin B1 and Ochratoxin A in Cereals by a Novel Electrochemical Aptasensor Using Metal-Organic Framework as Signal Carrier.

Foods. 2024-7-10

[6]
Food Safety Aspects of Breeding Maize to Multi-Resistance against the Major , , ) and Minor Toxigenic Fungi ( spp.) as Well as to Toxin Accumulation, Trends, and Solutions-A Review.

J Fungi (Basel). 2024-1-4

[7]
Advancements in Sample Preparation Methods for the Chromatographic and Mass Spectrometric Determination of Zearalenone and Its Metabolites in Food: An Overview.

Foods. 2023-9-25

[8]
T-2 and HT-2 Toxins: Toxicity, Occurrence and Analysis: A Review.

Toxins (Basel). 2023-7-29

本文引用的文献

[1]
Optimization of the QuEChERS-Based Analytical Method for Investigation of 11 Mycotoxin Residues in Feed Ingredients and Compound Feeds.

Toxins (Basel). 2021-10-29

[2]
Development and Validation of QuEChERS Followed by UHPLC-ToF-MS Method for Determination of Multi-Mycotoxins in Pistachio Nuts.

Molecules. 2021-9-23

[3]
Trace analysis and identification of 33 sulfonamides and sulfonamide potentiators in eggs by ultrahigh-performance liquid chromatography coupled with quadrupole-high-field orbitrap high-resolution mass spectrometry.

Anal Methods. 2021-10-8

[4]
Biosensors for Deoxynivalenol and Zearalenone Determination in Feed Quality Control.

Toxins (Basel). 2021-7-17

[5]
Development of a LC-MS/MS Method for the Simultaneous Determination of the Mycotoxins Deoxynivalenol (DON) and Zearalenone (ZEA) in Soil Matrix.

Toxins (Basel). 2021-7-7

[6]
High-Throughput Analysis of Aflatoxins in Cereals, Nuts, and Processed Products Involving Automated Immunoaffinity Cleanup and Inline HPLC-Fluorescence Detection.

J AOAC Int. 2021-12-11

[7]
Development and evaluation of multiplex PCR for detection of T-2 and zearalenone producing Fusarium spp.

Lett Appl Microbiol. 2021-9

[8]
Survey of aflatoxins and ochratoxin A contamination in spices by HPLC-based method in Shiraz, Southern of Iran.

Environ Sci Pollut Res Int. 2021-8

[9]
Molecular and HPLC-based approaches for detection of aflatoxin B and ochratoxin A released from toxigenic Aspergillus species in processed meat.

BMC Microbiol. 2021-3-14

[10]
Detection of Aflatoxins in Different Matrices and Food-Chain Positions.

Front Microbiol. 2020-8-14

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