François Cindy, Bonafé Arthur, Roubille Camille, Roubille François, Dupuy-Bonafé Isabelle, Millot Sarah
Département Fonction-Dysfonction, Imagerie et Biomatériaux, Centre de Soins d'Enseignement et de Recherche Dentaires, 34080 Montpellier, France.
PhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, 34295 Montpellier, France.
J Clin Med. 2022 Nov 19;11(22):6845. doi: 10.3390/jcm11226845.
Obstructive sleep apnea is a potentially dangerous condition with significant risks of comorbidities if left untreated. It represents a cardiovascular risk factor in the general population, and a higher prevalence is observed in patients already suffering from cardiovascular diseases. The gold standard treatment, continuous positive airway pressure, is not always accepted or tolerated. The mandibular advancement device represents an alternative treatment that we propose to implement in our study. The objective here is to first present a brief review of the topic. Due to poor evidence in the field, we propose a pilot study to evaluate the effect of a mandibular advancement device in patients with cardiovascular disease who are not treated for their sleep pathology in order to improve their therapeutic management.
阻塞性睡眠呼吸暂停是一种潜在危险的病症，如果不进行治疗，会有显著的合并症风险。它是普通人群中的一种心血管危险因素，在已经患有心血管疾病的患者中患病率更高。金标准治疗方法，即持续气道正压通气，并非总是能被接受或耐受。下颌前移装置是一种替代治疗方法，我们建议在我们的研究中采用。这里的目的是首先对该主题进行简要综述。由于该领域证据不足，我们建议开展一项试点研究，以评估下颌前移装置对未治疗睡眠疾病的心血管疾病患者的效果，从而改善他们的治疗管理。
