Department of Pathology and Laboratory Medicine, Mayo Clinic College of Medicine and Science, Jacksonville, FL, USA.
The Bolles High School, Jacksonville, FL, USA.
Int J Surg Pathol. 2023 Aug;31(5):795-800. doi: 10.1177/10668969221138860. Epub 2022 Nov 27.
Thyroid cancers exist in multiple forms. Papillary and follicular carcinomas of the thyroid are often referred to as well-differentiated thyroid cancers. Well-differentiated thyroid cancers rarely present as a distant metastatic cancer on initial diagnosis. Papillary thyroid cancer tends to have a good prognosis; however, if distant metastasis of PTC is present, there is usually a poor clinical outcome with a less favorable prognosis. In this study, we report a 90-year-old female who presented with right-sided abdominal discomfort. A renal ultrasound revealed bilateral upper pole renal masses. A percutaneous biopsy was ordered, and the microscopic examination revealed bilateral renal metastasis with a follicular variant of papillary thyroid carcinoma. The patient underwent thyroidectomy and sustained radiation therapy for her bilateral renal metastases. She died 6 years after her initial diagnosis, due to sepsis. This is the second study in literature to report bilateral renal metastasis of follicular variant of papillary thyroid cancer.
甲状腺癌有多种类型。甲状腺乳头状癌和滤泡状癌通常被称为分化良好的甲状腺癌。分化良好的甲状腺癌在初始诊断时很少表现为远处转移性癌症。甲状腺乳头状癌的预后通常较好；然而，如果存在 PTC 的远处转移，通常临床结局较差，预后也较差。在本研究中，我们报告了一例 90 岁女性，表现为右侧腹部不适。肾脏超声显示双侧肾上极肿块。行肾穿刺活检，显微镜检查显示双侧肾转移，伴甲状腺滤泡状癌。患者行甲状腺切除术，并对双侧肾转移灶进行放疗。她在最初诊断后的 6 年内死于脓毒症。这是文献中第二例报告的甲状腺滤泡状癌的双侧肾转移病例。
