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秘鲁前列腺癌死亡率:2003 年至 2017 年的更新数据。

Prostate Cancer Mortality in Peru: An Update from 2003 to 2017.

机构信息

Cancer Research Networking, Scientific University of the South, Lima, Peru.

Latin American Network for Cancer Research (LAN-CANCER), Lima, Peru.

出版信息

Asian Pac J Cancer Prev. 2022 Nov 1;23(11):3623-3628. doi: 10.31557/APJCP.2022.23.11.3623.

DOI:10.31557/APJCP.2022.23.11.3623
PMID:36444573
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9930958/
Abstract

OBJECTIVE

We estimated the mortality trends for prostate cancer in Peru and its geographical areas between 2003 and 2017.

MATERIAL AND METHODS

We obtained recorded prostate cancer deaths from the Peruvian Ministry of Health Database between 2003 and 2017. Age-adjusted mortality rates per 100,000 men-year were computed with the direct method using the world standard SEGI population. We estimated the annual percent change (APC) using the Joinpoint regression program.

RESULTS

A total of 38,617 prostate cancer deaths were reported between 2003 and 2017, with a mortality rate ranging from 18.21 to 19.94 deaths per 100,000 men-year. Since 2006, Peru has experienced a decrease of 2.2 deaths per year, whereas the mortality rate in the coastal region has declined by 2.9% per year.  The highlands and rainforest regions showed stable trends throughout the entire study period. According to provinces, only Moquegua had a significant decrease (APC: -6.0, 95%CI: -11.4, -0.2, p<0.05) from 2003 to 2017.

CONCLUSIONS

Although mortality rates are decreasing, there is a high mortality burden by prostate cancer in Peru and by geographical regions, being mostly concentrated in the coastal region. The rainforest provinces deserve the most attention. Our findings suggest wide health care disparities among the different regions of Peru that need greater public health attention to reduce the burden of mortality by prostate cancer.

摘要

目的

我们估计了 2003 年至 2017 年间秘鲁及其地区前列腺癌的死亡率趋势。

材料和方法

我们从秘鲁卫生部数据库中获取了 2003 年至 2017 年间记录的前列腺癌死亡病例。使用世界标准 SEGI 人口直接法计算每 10 万男性年的年龄调整死亡率。我们使用 Joinpoint 回归程序估计了年变化百分比(APC)。

结果

2003 年至 2017 年间共报告了 38617 例前列腺癌死亡病例,死亡率范围为每 10 万男性年 18.21 至 19.94 例。自 2006 年以来,秘鲁每年减少 2.2 例死亡,而沿海地区的死亡率每年下降 2.9%。高地和雨林地区在整个研究期间呈现稳定趋势。按省份划分,只有莫克瓜(Moquegua)自 2003 年至 2017 年呈显著下降趋势(APC:-6.0,95%CI:-11.4,-0.2,p<0.05)。

结论

尽管死亡率呈下降趋势,但秘鲁和各地区的前列腺癌死亡率仍然很高,主要集中在沿海地区。雨林地区需要特别关注。我们的研究结果表明,秘鲁不同地区之间存在广泛的医疗保健差距,需要更多的公共卫生关注,以减轻前列腺癌死亡率的负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ce/9930958/a68bc5ebc0a2/APJCP-23-3623-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ce/9930958/2d1a1135f3f6/APJCP-23-3623-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ce/9930958/a68bc5ebc0a2/APJCP-23-3623-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ce/9930958/2d1a1135f3f6/APJCP-23-3623-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31ce/9930958/a68bc5ebc0a2/APJCP-23-3623-g002.jpg

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Prostate cancer mortality rates in Peru and its geographical regions.秘鲁及其地区的前列腺癌死亡率。
BJU Int. 2019 Apr;123(4):595-601. doi: 10.1111/bju.14578. Epub 2018 Oct 31.
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