Matsuo Koji, Yoneki Kei, Tatsuki Hiroaki, Mibu Kazuhiro, Furuzono Kento, Kobayashi Kikka, Yasuda Shiori, Tamiya Seiji
Department of Rehabilitation, Sagamihara Kyodo Hospital.
Department of Rehabilitation Sciences, Graduate School of Medical Sciences, Kitasato University.
Int Heart J. 2022;63(6):1141-1149. doi: 10.1536/ihj.22-207.
Electrical muscle stimulation (EMS) is expected to be considered as an add-on therapy for the usual rehabilitation of patients with chronic heart failure (HF). However, it remains unclear whether EMS can reduce muscle volume loss in patients with acute HF (AHF) immediately after hospitalization. Therefore, the aim of this study was to investigate if EMS could reduce the lower-limb muscle volume loss in patients with AHF. In this single-center, retrospective, observational study, lower-limb skeletal muscle volume, quadriceps muscle layer thickness, and clinical events (worsening HF or kidney function) were evaluated in 45 patients with AHF (mean age, 77.4 ± 11.6 years, 31 males). All patients underwent EMS on the right leg, in addition to usual rehabilitation, for 20 minutes per day, 5 days per week, for 2 weeks. A two-factor (time × leg) analysis of variance was performed to compare the difference between the right leg (usual rehabilitation and EMS) and left leg (usual rehabilitation only). The skeletal muscle mass decreased by 11.6% ± 19.7% from baseline in the right leg and by 20.4% ± 16.1% in the left leg (interaction; F = 4.54, P = 0.036). The quadriceps muscle layer thickness decreased by 10.2% ± 7.1% from baseline in the right leg and by 13.5% ± 6.0% in the left leg (interaction; F = 10.50, P = 0.002). No clinical events were related to EMS. Results showed that EMS combined with usual rehabilitation for patients with AHF has the potential to inhibit muscle volume loss.
电肌肉刺激（EMS）有望被视为慢性心力衰竭（HF）患者常规康复的辅助治疗方法。然而，目前尚不清楚EMS是否能在急性心力衰竭（AHF）患者住院后立即减少肌肉量的损失。因此，本研究的目的是调查EMS是否能减少AHF患者的下肢肌肉量损失。在这项单中心、回顾性、观察性研究中，对45例AHF患者（平均年龄77.4±11.6岁，男性31例）的下肢骨骼肌量、股四头肌层厚度和临床事件（心力衰竭或肾功能恶化）进行了评估。所有患者除接受常规康复治疗外，右腿还接受了EMS治疗，每天20分钟，每周5天，共2周。采用双因素（时间×腿）方差分析比较右腿（常规康复和EMS）和左腿（仅常规康复）之间的差异。右腿骨骼肌质量较基线下降了11.6%±19.7%，左腿下降了20.4%±16.1%（交互作用；F=4.54，P=0.036）。股四头肌层厚度右腿较基线下降了10.2%±7.1%，左腿下降了13.5%±6.0%（交互作用；F=10.50，P=0.002）。没有临床事件与EMS相关。结果表明，EMS联合常规康复治疗对AHF患者有抑制肌肉量损失的潜力。
