新冠病毒mRNA疫苗接种后慢性免疫性血小板减少症患儿血小板计数迅速下降：病例报告
Quick drop of platelet counts in children with chronic immune thrombocytopenia after COVID-19 mRNA vaccination: case reports.
作者信息
Lassandro Giuseppe, Carriero Francesco, Palladino Valentina, Del Vecchio Giovanni Carlo, Giordano Paola
机构信息
Department Interdisciplinary of Medicine, Pediatric Unit "B. Trambusti", University of Bari "Aldo Moro", Bari, Italy.
出版信息
Clin Exp Vaccine Res. 2022 Sep;11(3):290-293. doi: 10.7774/cevr.2022.11.3.290. Epub 2022 Sep 30.
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia. Many viruses and some vaccines have been identified as triggering the autoimmune process, including parvovirus, human immunodeficiency virus, Epstein-Barr virus, rubella, and measles. However, ITP in association with coronavirus disease 2019 (COVID-19) vaccination has not been reported so far. We describe the cases of two young girls affected by ITP presenting a quick reduction of platelet count after receiving Pfizer-BioNTech COVID-19 vaccine.
免疫性血小板减少症（ITP）是一种以孤立性血小板减少为特征的自身免疫性疾病。许多病毒和一些疫苗已被确定为触发自身免疫过程的因素，包括细小病毒、人类免疫缺陷病毒、爱泼斯坦-巴尔病毒、风疹和麻疹。然而，迄今为止尚未有与2019冠状病毒病（COVID-19）疫苗接种相关的ITP报道。我们描述了两名患ITP的年轻女孩在接种辉瑞-BioNTech COVID-19疫苗后血小板计数迅速下降的病例。
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